Lauroyl chloride

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.11 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.036 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.011 mg/L

Assessment factor:

100

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

2 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.499 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.05 mg/kg sediment dw

Extrapolation method:

assessment factor

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

9.89 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Additional information

Due to the rapid hydrolysis of lauroyl chloride, the environmental assessment is mainly based on its hydrolysis product lauric acid (CAS 143-7-7) and its sodium salt (sodium laurate, CAS 629-25-4). Results are available for fish (sodium laurate: 96-h LC50 = 11 mg/L, Onitsuka et al., 1989; 28-d NOEC (mortality) = 2 mg/L, van Egmond et al., 1999), invertebrates (lauric acid: 48-h EC50 = 3.6 mg/L; sodium laurate: 21-d NOEC = 100 mg/L, Radix et al., 2000) and algae (sodium laurate, 72-h ErC50 = 60 mg/L, 72-h ErC10 = 1.1 mg/L; 72-h NOEC = 5 mg/L, Radix et al., 2000).

Effect values of the hydrolysis product HCl (7647 -01 -0) were not considered in the ecotoxicological evaluation of the substance since the observed toxicity was not due to intrinsic properties of the molecule, but is due to pH effects.

 

 

Official classification regarding environmental hazards:

 

Aquatic compartment

 

In accordance with Regulation (EC) No 1272/2008 Annex VI Table 3.1 or Table 3.2, lauroyl chloride: no data found.

 

In accordance with Regulation (EC) No. 1272/2008 Annex VI Table 3.1 or Table 3.2, lauric acid: no data found.

 

In accordance with Regulation (EC) No. 1272/2008 Annex VI Table 3.1 or Table 3.2, sodium laurate: no data found.

 

 

Self-classification:

 

Aquatic compartment

 

Following DSD/DPD, the substance is to be classified as dangerous for the environment. The lowest LC50/EC50 value is 3.6 mg/L (lauric acid, CAS 143-07-7). The hydrolysis product lauric acid is readily biodegradable (weight of evidence approach), but the BCF was experimentally determined to be 252.

 

 

Following CLP (GHS-EU), the substance is not to be classified as acutely hazardous to the aquatic environment, since the lowest acute effect value is > 1 mg/L.

 

Chronic data are available for fish, Daphnia and algae (NOEC > 1 mg/L), therefore classification is based on the available chronic data. The data available for chronic classification are conclusive but not sufficient for classification. The chronic data indicate that lauroyl chloride is not to be classified as hazardous to the aquatic environment. Lauric acid is readily biodegradable.The BCF was experimentally determined to be < 500. Therefore, the substance is not be classified as chronically hazardous to the environment.

 

 

Atmospheric compartment

 

The test substance is not listed in Annex 1 of Regulation (EC) 2037/2000 on substances that deplete the ozone layer.

 

 

The test substance does not belong to the greenhouse gases listed in P Forster, PV Pamaswamy et al. Changes in Atmospheric Constituents and Radiative Forcing. In: Climate Change 2007: The Physical Basis. Contribution of Working Goup 1 to the Fourth Assessment Report of the Intergovernmental Panel on climate Change.