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EC number: 215-578-1 | CAS number: 1333-07-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
op-TSA is assumed to be hydrolytically stable from a guideline study with o-TSA.
A SCAS test, valid with restrictions, is available. During the twenty-one day biodegradation phase of the study op-TSA was 92.9% biodegraded when initially present at 56.9 ppm. The test material is considered to undergo rapid primary biodegradation based upon this study. Examination of the microbial population data shows no evidence of adverse effects of the test compound upon the microflora present in the sludge.
op-TSA is inherently biodegradable.
o/p-TSA has a low log Kow and is highly soluble in water, therefore adsorption to soil and sediment is not expected to take place. Therefore, biodegradation in soil and sediment as well as an adsorption/desorption studie are waived.
Bioaccumulation studies with o-TSA and p-TSA gave the following results:
A study with o-TSA was performed according to OECD guideline 305C with Cyprinus carpio at 0.3 and 3 mg/L. After 42 days the BCF vaues were 0.4 to 0.9 at 3 mg/L and < 2.6 at 0.3 mg/L. This shows that o-TSA does not have a potential to bioaccumulate.
A study for p-TSA with Oncorhynchus mykiss was performed with Chloramine-T (CAS 127 -65 -1). As p-TSA was detected and actually BCF values were calculated for p-TSA, this study can be used for p-TSA.
The kinetic whole body BCF as calculated from the accumulation and depuration from fingerling half-lives using the p-TSA equivalent concentration (worst-case). The k1/k2 ratio as calculated according to OECD guideline 305 is 2.2 based on LSC (worst case).
As op-TSA is a mixture of o-TSA and p-TSA it can be concluded that op-TSA does not have a potential to bioaccumulate either.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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