Registration Dossier
Registration Dossier
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EC number: 203-891-6 | CAS number: 111-64-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysis product: Octanoic acid: With high probability acutely not harmful to aquatic invertebrates.
Hydrolysis product: HCl: Acutely very toxic to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
No data on the toxicity of octanoyl chloride is available. However, since the test substance rapidly hydrolyses in water invertebrates are mainly exposed to the hydrolysis product, octanoic acid.
Octanoic acid is not acutely harmful to Daphnia magna in a 48-hour exposure scenario (48-h EC50 (nominal) = 550 mg/L; Henkel, 2001). The test was performed similar to OECD 202, test concentrations were not analytically verified.
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD 2002).
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