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EC number: 214-730-4 | CAS number: 1191-16-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No experimental toxicokinetic data are available for prenyl acetate.
Based on its physicochemical properties, i.e. small molecular weight, LogPow and good water solubility at room temperature (MW=128.2, Log Pow = 2.0, water solubility = 4300 mg/L), prenyl acetate is considered to show a good bioavailability via the dermal and oral route. On the basis of the low vapour pressure at room temperature (vapour pressure = 260 Pa), the exposure via inhalation of prenyl acetate as a vapour is low. Oral bioavailability of prenyl acetate is qualitatively indicated by observed mortalities and clinical findings in acute oral toxicity studies in rats. Furthermore, clinical signs found after single dermal application in rabbits are indicative for bioavailability via the dermal route.
Concerning metabolism and elimination, prenyl acetate is expected to hydrolyze to prenol and acetic acid. In animals hydrolysis of aliphatic esters is catalyzed by classes of enzymes recognized as carboxylesterases or esterase. Terpenoid alcohols formed in the gastrointestinal tract are then rapidly absorbed. Following hydrolysis, metabolization by alcohol oxidation, omega-oxidation, hydration, hydrogenation and conjugation to form oxygenated polar metabolites are expected, which are then excreted.
Based on the information given above, there is no evidence for a bioaccumulative potential of prenyl acetate.
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