Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 240-722-5 | CAS number: 16673-34-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1980
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study performed in 1980 did not follow the OECD but it is comparable to guidelines/standards.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 980
- Report date:
- 1980
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- FDA guidelines
- GLP compliance:
- no
Test material
- Reference substance name:
- N-[2-[4-(aminosulphonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide
- EC Number:
- 240-722-5
- EC Name:
- N-[2-[4-(aminosulphonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide
- Cas Number:
- 16673-34-0
- Molecular formula:
- C16H17ClN2O4S
- IUPAC Name:
- 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- Californian
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not specified
- Amount / concentration applied:
- 100 mg
- Observation period (in vivo):
- 1, 7, 24, 48, 72 hour after application
- Number of animals or in vitro replicates:
- 6
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information
- Conclusions:
- The substance is sligthly irritant for the eyes.
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