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EC number: 287-476-5 | CAS number: 85535-84-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
The reproductive toxicity of a C10-12 chlorinated paraffin (58% chlorination) was assessed in a GLP study performed using a protocol similar to OECD Guideline 206, in which Mallard ducks were fed the SCCP in the diet for 22 weeks at a concentration of up to 1000 mg/kg diet. A decrease in 14-day embryo viability was seen at the top dose, but no effects (including egg shell cracking, egg weight, egg shell thickness, and hatchability) were seen at 166 or 28 mg/kg diet. Therefore, the reproduction NOEC is considered to be 166 mg/kg diet and the parental NOEC 1000 mg/kg diet (Shults et al. 1984).
Key value for chemical safety assessment
Additional information
In a reproduction test, performed using a protocol similar to OECD Guideline 206, and to GLP, groups of 20 pairs of adult Mallard ducks (Anas platyrhynchos) were fed a C10-13 chlorinated paraffin (58% chlorinated) in the diet at 28, 166 or 1000 mg/kg diet. Treatment duration was 22 weeks, including a 9-week pre-egg-laying period without photostimulation, a 3-week pre-egg-laying period with photostimulation and a 10-week egg-laying period with photostimulation. The young were observed for 14 days (note the young were not fed with the test substance). Endpoints recorded included adult mortality, egg production, number of cracked eggs, egg shell thickness, viability, hatchability and effects on young birds.
No treatment-related effects were seen on adult mortality, appearance, behaviour, body weight or food consumption. A decrease in 14-day embryo viability (statisitcally significant at weeks 3 and 6) and a decrease in egg shell thickness (statistically significant but still within the normal range) were seen at the highest concentration only. There were no other treatment-related effects on reproductive endpoints, including number of eggs laid, number of cracked eggs, mean egg weight; number of live 21-day embryos, hatchlings or 14-day old survivors; or hatchling appearance, behaviour or body weight.
A decrease in 14-day embryo viability was seen in a reproduction toxicity test in which Mallard ducks were fed a C10-13 chlorinated paraffin (58% chlorinated) in the diet for 22 weeks at a concentration of 1000 mg/kg diet; no effects were seen at 166 or 28 mg/kg diet. Therefore, the reproduction NOEC was 166 mg/kg diet and the parental NOEC was 1000 mg/kg diet.
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