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EC number: 441-420-8 | CAS number: 113889-23-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The Ready Biodegradability of Cyclobutanate was determined by the CO2 Evolution Test according to OECD TG 301B under GLP. The concentration tested was 10 mg C/l, with an activated sludge concentration of 30 mg suspended solids/l. The validity of the test was confirmed with control solutions with inoculum and the standard material, sodium benzoate and a toxicity control which attained 73% degradation after 28 days. This confirming that the test material was not toxic to the sewage treatment micro-organisms used in the study. The total biodegradation percentage after 28 days is 43%, including the inorganic carbon present in the solution on day 28 and the carry-over in the second absorber. Cyclobutanate is not readily biodegradable under the test conditions of OECD Guideline No 301B.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
In addition, a ready biodegradability test according to OECD TG 301C (2015, MITI test, based on oxygen consumption) was performed. The test item concentration was 100 mg/l and the activated sludge 30 mg/l, The substance showed 34% degradation after 28 days. Because the substance was not readily biodegradable the key metabolites were also determined, which was Cycla-alcohol (Cas no: 3385 -61-3). No Cyclobutanate or butanoic acid was found. Overall, after 28 days: 100% Cyclobutanate was degraded: 34% was degraded to CO2 (likely the butanoic acid chain) and 66% remained as Cycla-alcohol, completing the mass balance.
In another ready biodegradation study also according to OECD TG 301C (2002) 22% biodegradation was found and no Cyclobutanate; degradation products were seen but not identified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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