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EC number: 271-239-8 | CAS number: 68526-91-0 A complex combination of hydrocarbons produced by the distillation of products from the hydrogenation of isotridecanal from the hydroformylation of dodecene. It consists predominantly of C13-14 primary aliphatic alcohols, C22-28 dimer alcohols, C26 acetals and esters, and C>10 acid sodium salts and boils in the range of approximately 250°C to 450°C (482°F to 842°F).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Assessment of the Toxicokinetic Behaviour for Oxooel 13 (CAS-No. 68526-91-0)
There were no studies available in which the toxicokinetic properties of Oxooel 13 were investigated.
Oxooel 13 (molecular weight of 198.35 g/mol) is a clear colourless liquid, which is soluble in water(measured water solubility: 10 - 14 mg/l at 20 °C (BASF SE, 2009); see “water solubility”).The estimated log Pow is 4.9 at 20 °C (BASF SE, 2009; see “partition coefficient”), indicating that a general accumulation of Oxooel 13 is possible.
Due to the physico-chemical properties, a general accumulation of the test item might be possible.
Absorption
In an acute oral and dermal toxicity study, rats were once administered Oxooel 13. In both studies neither mortalities nor signs of systemic toxicity were observed in doses of 2000 mg/kg bw and higher (BASF AG, 1982; see “acute oral toxicity”; BASF SE, 2009; see “acute dermal toxicity”), indicating primarily a low acute toxicity.
In a subacute study in rats signs of general systemic toxicity (hematologic changes) were observed at a dose level of 1000 mg/kg bw/d (BASF SE, 2010).Therefore, bioavailability of Oxooel 13 after oral administration is indicated.
Additionally, due to the physico-chemical properties described above (molecular weight, water solubility, logPow), an uptake via the GI tract and a dermal uptake is possible.
Oxooel 13 has a comparably low vapour pressure of 0.3 hPa at 20°C (BASF SE, 2009, see “vapour pressure”). Therefore, exposure of the test item via the inhalative route is not assumed.
Due to the experimental low acute oral and dermal toxicity, no quantitative assessment of the absorption potential of Oxooel 13 in humans can be made.
Metabolism
The signs of general systemic toxicity (hematologic changes) observed at a dose level of 1000 mg/kg bw/d in the subacute study in rats (BASF SE, 2010) suggests bioavailability of Oxooel 13 after oral administration.
The test item shows skin sensitisation in the LLNA.This implies protein binding. But information about potential metabolites is not available.
Studies on genotoxicity (Ames-Test, HPRT-Test) gave no indication for toxic metabolism.
Excretion
Given that there is no information about potential metabolites available, it can only be assumed from the physico-chemical properties that Oxooel 13 is possible to accumulate in the fatty tissue.
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