Registration Dossier
Registration Dossier
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EC number: 266-257-8 | CAS number: 66215-27-8
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1998/03/24 to 1998/04/23
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- This experimental study report is reliable as it has been conducted by a trusted laboratory, under GLP and following standard operating procedure (SOP 209/5).
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- SOP 209/5
- GLP compliance:
- yes
- Key result
- Medium:
- other: Hexane
- Solubility:
- < 1 mg/L
- Temp.:
- 25 °C
- Key result
- Medium:
- other: Dichloromethane
- Solubility:
- 210 mg/L
- Temp.:
- 25 °C
- Key result
- Medium:
- toluene
- Solubility:
- 11 mg/L
- Temp.:
- 25 °C
- Key result
- Medium:
- n-octanol
- Solubility:
- 1.5 g/L
- Temp.:
- 25 °C
- Key result
- Medium:
- methanol
- Solubility:
- 17 g/L
- Temp.:
- 25 °C
- Key result
- Medium:
- ethyl acetate
- Solubility:
- 660 mg/L
- Temp.:
- 25 °C
- Key result
- Medium:
- acetone
- Solubility:
- 1.4 g/L
- Temp.:
- 25 °C
- Test substance stable:
- not determined
- Conclusions:
- The solubility of the test substance at 25°C is 1.4 g/L in acetone; 660mg/L in ethyl acetate; 17 g/L in methanol; 1.5 g/L in octanol; 11 mg/L in toluene; < 1 mg/L in hexane and 210 mg/L in dichloromethane.
- Executive summary:
The solubility of test substance in organic solvents was determined in accordance with the standard operating procedure 209/5. The solubility of the test substance at 25°C is 1.4 g/L in acetone; 660mg/L in ethyl acetate; 17 g/L in methanol; 1.5 g/L in octanol; 11 mg/L in toluene; < 1 mg/L in hexane and 210 mg/L in dichloromethane.
Reference
Description of key information
The solubility of the test substance at 25°C is: 1.4 g/L in acetone; 660mg/L in ethyl acetate; 17 g/L in methanol; 1.5 g/L in octanol; 11 mg/L in toluene; < 1 mg/L in hexane; 210 mg/L in dichloromethane, Standard operating procedure 209/5, Stulz J 1998
Key value for chemical safety assessment
- At the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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