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Diss Factsheets
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EC number: 224-339-0 | CAS number: 4316-74-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: "Regulations Governing Laboratory Certification and Standards of Performance", New Jersey Administrative Code, 7:18
- Version / remarks:
- as amended July 1984
- Deviations:
- not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- All surfactants were samples of commercially available products. Toxicities of the individual surfactants, their mixtures and reactor effluents were determined by 48h, daily static renewal tests with Mysidopsis bahia (mysids). This marine species was recently introduced as a test organism for monitoring the toxicities of wastewater treatment plant effluents and other discharges to the environment in New Jersey and Florida. Tests were performed according to the procedure in “Regulations Governing Laboratory Certification and Standards of Performance”, New Jersey Administrative Code, 7:18, as amended July 1984. Toxicity results were calculated by a probit method and were reported as a concentration (for untreated products) or a dilution (for effluents) resulting m the death of 50% of the test organisms (LC50).
- Analytical monitoring:
- not specified
- Test organisms (species):
- Americamysis bahia (previous name: Mysidopsis bahia)
- Test type:
- static
- Water media type:
- saltwater
- Total exposure duration:
- 48 h
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 12.8 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- The values were determined during the investigation and are based on a single analysis.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC50 (48 h) of methyl oleoyl taurate is 12.8 mg/L for Americamysis bahia.
- Executive summary:
The publication reports the toxicity of ethoxylated surfactants, including methyl oleoyl taurate as a reference. The toxicity was determined using Americamysis bahia according to the New Jersey Administrative Code, 7:18 as amended 1984. The LC50 (48 h) of methyl oleoyl taurate is 12.8 mg/L.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- The estimation is based on EPI Suite, ECOSAR v1.11. Two models are available, the estimation from the class (Aliphatic Amines-acid) and the Baseline Toxicity (neutral organic structure analysis relationship).
- Principles of method if other than guideline:
- The estimation is based on ECOSAR v1.11. Two models are available, the estimation from the Class (Aliphatic Amines-acid) and the Baseline Toxicity (neutral organic structure analysis relationship)
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Calculation is based on the structure of N-methyltaurinate
- Name of test material (as cited in study report): Ethanesulfonic acid, 2- (methylamino)-, monosodium salt - Analytical monitoring:
- not required
- Vehicle:
- not specified
- Test organisms (species):
- other: Daphnids
- Test type:
- other: estimation by calculation
- Water media type:
- not specified
- Total exposure duration:
- 48 h
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Remarks:
- (Aliphatic Amines-acid)
- Effect conc.:
- 29 688.508 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- other: estimation by calculation
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Remarks:
- (Neutral Organic SAR)
- Effect conc.:
- 1 030 000 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- other: estimation by calculation
- Remarks on result:
- other:
- Remarks:
- Note: Chemical may not be soluble enough to measure this predicted effect.
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The lowest calculated LC50 (48 h) of sodium N-methyltaurinate for daphnia is 29.69 g/L.
- Executive summary:
The lowest calculated LC50 (48 h) of sodium N-methyltaurinate for daphnia is 29.69 g/L, which reflects low toxicity. Nevertheless, the estimation by calculation only provides an approximation and cannot replace empirical studies. The EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available.
Referenceopen allclose all
Description of key information
Using EPI Suite (ECOSAR), an LC50 (48 h) of sodium N-methyltaurinate of 29.69 g/L was calculated for daphnids. Nevertheless, the estimation by calculation only provides an approximation and cannot replace empirical studies. The publication by Patoczka et al. reports an LC50 (48 h) of 12.8 mg/L for read-across substance methyl oleoyl taurate, which was determined according to the New Jersey Administrative Code, 7:18 using Americamysis bahia.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 12.8 mg/L
Additional information
Using EPI Suite (ECOSAR), an LC50 (48 h) of sodium N-methyltaurinate of 29.69 g/L was calculated for daphnids. Nevertheless, the estimation by calculation only provides an approximation and cannot replace empirical studies. The publication by Patoczka et al. reports an LC50 (48 h) of 12.8 mg/L for read-across substance methyl oleoyl taurate, which was determined according to the New Jersey Administrative Code, 7:18 using Americamysis bahia. The empirical value for methyl oleoyl taurate is lower than the estimated value for sodium N-methyltaurinate. The EPA recommends that EPI Suite is a screening-level tool and should not be used if acceptable measured values are available. Nevertheless, both the empirical and estimated values are rather high, so that the studies on the read-across substance support the results of the EPI Suite estimation. Therefore, we conclude that the aquatic toxicity data of methyl oleoyl taurate provide a reasonable measure to estimate the toxicity of sodium N-methyltaurinate on invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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