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EC number: 435-410-2 | CAS number: 351491-23-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 02 May 2000 to 23 August 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- distillation method
- Key result
- Boiling pt.:
- > 70.3 - < 72.8 °C
- Atm. press.:
- 0.13 Pa
- Decomposition:
- yes
- Decomp. temp.:
- > 70 - < 73 °C
- Conclusions:
- The test item boils with a partial decomposition between 70.3°C and 72.8°C at 0.13 Pa
- Executive summary:
The boiling point of the test item was determined with the distillation method according to recognised guideline and GLP. No deviation from the guideline was observed during the study.
A preliminary test was performed to determine the experimental conditions to be used in the main tests. Based on the results obtained in the main tests, the boiling range of the test item is 70.3°C and 72.8°C at reduced pressure (0.13 Pa). While boiling, the test item is partially decomposed.
Reference
In the preliminary test, in a micro-distillation apparatus, a small amount of the test substance in a bottle was heated. The test substance was heated to 199°C at an atmospheric pressure of 101.89 kPa at which the test substance started to boil. The test substance started to distil at a distillation temperature of 83.5°C. The test substance distilled dropwise while the distillation temperature raised to 207.5°C. The distillation stopped and the test substance (residue) decomposed to a black/brown substance. Because the test substance decomposed above 60°C, the boiling temperature was determined under reduced pressure.
In the two main tests, a micro-distillation apparatus was used. The test substance was heated to 135 or 125°C under reduced pressure (0.13Pa) at which the substance started to boil. At a distillation temperature 70°C or 70.5°C the test substance started to distil dropwise. The test substance was distilled as a whole at a distillation temperature of 73°C or 72.5°C.
In order to determine if the test substance was decomposed during the test, the distillate was analysed by mean of HPLC. For this purpose, a certain amount of the distillate obtained in the main tests was dissolved in methanol. The solutions were analysed by means of HPLC. The analytical method used was calibrated for quantification of the test item between 1.3 and 212.9 mg/l. The recovery percents of the distillate obtained in the main tests were 72% and 56%. These results proved that partial decomposition of the test substance occurred during the test.
Description of key information
The boiling range of the test item was determined in an experimental key study of Klimisch validity 1.
Key value for chemical safety assessment
Additional information
The test item boils with a partial decomposition between 70.3°C and 72.8°C at 0.13 Pa
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