Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-069-1 | CAS number: 68002-54-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96 hour LL50 was > 100 mg/L and the NOELR 100 mg/L based on exposure to a WAF of the test material.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
This endpoint was addressed using a read across approach to structural analogues of the registered substance. Two key studies are provided, one on tall oil and one on ethanolamine. In this respect it is considered that the data submitted provides an adequate reflection of the test material.
A limit test was carried out to assess the acute toxicity potential of the read across substance distilled tall oil to Danio rerio in accordance with the standardised guideline OECD 203 under GLP conditions. The study was assigned a reliability score of 2 in accordance with the criteria of Klimisch (1997).
The fish were exposed to a 100 mg/L loading rate WAF of the test material for 96 hours under semi-static conditions. Fish were observed for any effects on mortality and additionally for any sub-lethal and behavioural effects.
No mortality was seen throughout the test period, nor were any sub-lethal effects noted.
Under the conditions of this study, the 96 hour LL50 was determined to be > 100 mg/L and the NOELR to be 100 mg/L based on exposure to a WAF of the test material. No classification of the test material is required in accordance with EU criteria.
The second key study investigates the acute toxicity potential of the read across substance ethanolamine to Cyprinus carpio in accordance with Directive 92/69/EEC, C.1 under GLP conditions. The study was assigned a reliability score of 2 in accordance with the criteria of Klimisch (1997).
The fish were exposed to nominal concentrations of 3, 10, 30, 100, 300 and 1000 mg/L for 96 hours under semi-static conditions.
None of the controls or fish exposed to 90 mg/L died. One fish exposed to 150 mg/L died between 72 and 96 hours. Two fish exposed to 280 mg/L died within 72 hours. All fish exposed to 500 and 900 mg/L were dead by 48 and 24 hours, respectively.
The high mortality within the upper concentration range may be attributable to the increased pH (maximum pH 10.2) caused by the test material.
Under the conditions of this study, the 96 hour LC50 of the test material was 349 mg/L (confidence limit 280 to 500 mg/L). The test material requires no classification in accordance with EU criteria.
Under the conditions of these studies, neither the tall oil nor ethanolamine component of the test material requires classification for acute toxicity. On this basis, and as a precautionary measure, the overall determination that will be carried forward for risk assessment of the registered substance will be the 96 hour LL50 of > 100 mg/L and NOELR of 100 mg/L based on exposure to a WAF of the test material.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.