Registration Dossier
Registration Dossier
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EC number: 610-545-1 | CAS number: 50588-42-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Read-across justification summary is attached to this endpoint summary.
Short description of key information:
Dienone did not show a mutagenic potential in a bacterial reverse mutation assay (Salmonella typhimurium: TA1535, TA1537, TA98, TA100 and Echerichia coli: WP2 (pKM101), WP2 uvrA (pKM101)) when tested up to the highest recommended dose level of 5.0 mg/plate in the absence or presence of extrinsic metabolic activation (rat liver S9 mix). Therefore, by read-across, didenac is not mutagenic.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Based on read-across to dienone, didenac is not classified as mutagenic according to the Directive 67/548/EEC or according to Regulation (EC) 1272/2008 (CLP).
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