Registration Dossier
Registration Dossier
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EC number: 642-783-7 | CAS number: 75279-53-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 August 2015 - 9 October 2015
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-(4-chloro-2-fluorophenyl)acetonitrile
- EC Number:
- 642-783-7
- Cas Number:
- 75279-53-7
- Molecular formula:
- C8 H5 Cl F N
- IUPAC Name:
- 2-(4-chloro-2-fluorophenyl)acetonitrile
- Test material form:
- other: solid
- Details on test material:
- Lot no. 280001T01O
Purity 100% (m/m)
Molecular formula C8H5ClFN
Molecular mass 169.59 g/mol
Theoretical oxygen demand 2.170 mg O2/mg
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Duration of test (contact time):
- ca. 28 d
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- -10
- Sampling time:
- 28 d
- Remarks on result:
- other: no
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- PAC-Nitrile is not biodegradable in the Manometric Respirometry Test 301 F within 28 days.
- Executive summary:
The biodegradability of PAC-Nitrile exposed to microorganisms derived from activated sludge of a
municipal sewage treatment plant was investigated under aerobic static exposure conditions.
No biodegradability of PAC-Nitrile based on O2 consumption was observed after 28 days as compared
to the theoretical oxygen demand (ThOD).
The procedure control sodium benzoate reached 83% biodegradation after 14 days, thus confirming
suitability of inoculum and test conditions.
PAC-Nitrile is not biodegradable in the Manometric Respirometry Test 301 F within 28 days.
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