Registration Dossier
Registration Dossier
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EC number: 215-903-7 | CAS number: 1448-36-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Predictions by two QSAR models are both: "non-mutagen".
They are considered as reliable based on the following issues:
- strongly similar compounds with known experimental value in the training set have been found.;
- similar molecules found in the training set have experimental values that agree with the predicted value;
- the accuracy of prediction for similar molecules found in the training set is good;
- all atom centered fragment of the compound have been found in the compounds of the training set.
Justification for selection of genetic toxicity endpoint
The QSAR predictions are deemed as equivalent for reliability. Therefore, the mutagenicity of the substance is assessed based on weight of evidence.
Short description of key information:
Predictions by two QSAR models are both: "non-mutagen"; the results appear to be reliable.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance should not be classified for mutagenicity
because of inconclusive data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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