Reaction mass of 4-(2-methylbutan-2-yl)phenol and 2,4-bis(2-methylbutan-2-yl)phenol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

19 September 2015 to 28 November 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Atm. press.:

1 013.25 hPa

Decomposition:

yes

Decomp. temp.:

> 200 °C

Remarks on result:

not determinable

Preliminary test

From 200°C upwards the weight of the sample decreased significantly. At 249°C the sample weight had decreased by 25%.

After the experiment it was observed that the test item was evaporated from the sample container.

 

Main study

An endothermic peak between 200°C and 300°C was observed. The extrapolated onset temperature of the peak was 261.55°C. The effect was most likely obtained due to boiling of the test item. After the experiment it was observed that the test item was evaporated from the sample container.

Experiment 2 was performed to determine the duplicate results of the test item. The temperature program was similar as the program of Experiment 1. Similar results as with Experiment 1 were obtained. The extrapolated onset of the second endothermic peak was 260.29°C After the experiment it was observed that the test item was evaporated from the sample container.

During experiment 3 a closed sample container and a repeated heating cycle were used to investigate the boiling peak. The second endothermic peak was observed at 263.04°C. It was not shifted to a higher temperature, which demonstrated that boiling of the test substance was not reason for the endothermic effect. After the experiment it was observed that the test item was evaporated from the sample container.

Conclusions:

Reaction and/or decomposition of Phenol, 1,1-dimethylpropyl derivs. was observed during DSC experiments at temperatures of > 200°C (> 473K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Executive summary:

The purpose of the study was to determine the physico-chemical properties for Phenol, 1,1-dimethylpropyl derivs.

 

The study was performed to the following guideline:

European Community (EC), EC no. 440/2008, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.2: “Boiling Temperature”, Official Journal of the European Union no. L142, May 31, 2008.

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no. 103: "Boiling Point", July 27, 1995.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7220: "Boiling Point/Boiling Range", August 1996.

 

Reaction and/or decomposition of Phenol, 1,1-dimethylpropyl derivs. was observed during DSC experiments at temperatures of > 200°C (> 473K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Description of key information

Key value not determinable due to decomposition/reaction in a GLP accredited laboratory study using DSC in accordance with OECD Guideline 103, EU Method A.2 and US EPA Procedure OPPTS 830.7220.  

Additional information

Reaction and/or decomposition of Phenol, 1,1-dimethylpropyl derivs. was observed during DSC experiments at temperatures of > 200°C (> 473K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.