Registration Dossier
Registration Dossier
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EC number: 463-070-5 | CAS number: 106966-25-0
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for test
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.20 (Daphnia magna Reproduction Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- -
- EC Number:
- 463-070-5
- EC Name:
- -
- Cas Number:
- 106966-25-0
- Molecular formula:
- C7H17N2O2Br
- IUPAC Name:
- 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide
Constituent 1
Sampling and analysis
- Details on sampling:
- - Concentrations: 1.0, 3.2, 10 and 32 mg/l (renewed 3 times per week)
- Sample storage conditions before analysis: room temperature in the dark
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Total exposure duration:
- 21 d
Test conditions
- Hardness:
- 112-144 mg/L CaCO3
- Test temperature:
- 20 degree of Celsius
- pH:
- 0.6
- Dissolved oxygen:
- 8.1 mg O2/L
- Nominal and measured concentrations:
- 1.0, 3.2, 10 and 32 mg/l (renewed 3 times per week)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 7.8 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- reproduction
- Remarks on result:
- other: 95% confidence limits of 4.7 - 13 mg/L
- Duration:
- 14 d
- Dose descriptor:
- EC50
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- immobilisation
- Remarks on result:
- other: 95% confidence limits of 41 - 63 mg/L
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 45 mg/L
- Nominal / measured:
- nominal
- Basis for effect:
- immobilisation
- Remarks on result:
- other: 95% confidence limits of 33 - 61 mg/L
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 3.2 mg/L
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 mg/L
- Basis for effect:
- immobilisation
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
