Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 447-010-5 | CAS number: 670241-72-2 ISONONYLBENZOAT
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Isononyl benzoate was tested for potential toxicity towards terrestrial organisms in an earthworm acute toxicity study and a plant toxicity study. Acute toxicity of the test item was low with LC50 earthworm > 1000 mg/kg and EC50 seedlings emergence for 3 plant species also > 1000 mg/kg soil dw. Effects in biomass were recorded with a NOEC (bodyweight earthworm) = 560 mg/kg and a NOEC = 32 mg/kg for the biomass parameter shoot height and shoot fresh weight in one plant species; the lowest biomass EC50 was 139 mg/kg for shoot fresh weight in oats.
The acute effects of isononyl benzoate on earthworm Eisenia fetida fetida Savigny were determined according to the OECD guideline 207 with the nominal concentrations of 100 - 180 - 320 - 560 - 1000 mg/kg soil dry weight (DW) over a test period of 14 days. 40 test organisms with a individual weight between 0.3 - 0.6 g, divided into four replicates, were tested per concentration, solvent control and control in artificial soil as described by the guideline. For statistical evaluation, the replicates of control and solvent control were pooled.
No mortality was observed up to and including the test item concentration 1000 mg/kg soil dw. The concentration with no observed effect (NOEC) of the test item with respect to loss of body weight and sublethal symptoms was found to be 560 mg/kg soil dw after 14 days of exposure. A summary of all effects in the tested concetrations is given in the table. The validity criteria of the test guideline were fullfilled.
LC50 (14d) > 1000 mg/kg soil dw
NOEC (14d) bodyweight = 560 mg/kg soil bw.
The phytotoxicity of the test item Isononyl benzoate to three terrestrial plant species was determined in a seedling emergence test over a period of 21 days, according to OECD Draft 208 (September 2003) with the nominal concentrations of 10 - 32 - 100 - 320 - 1000 mg/kg soil dry weight (dw). Test systems were one monocotyledon, oats (Gramineae), and two dicotyledons, soybean (Leguminosae) and rape (Brassicaceae). The test item was incorporated into the soil in which the seeds were sown. The test container were bottom watered with nutrient solution as needed. The toxic effects of the test item were determined on day 7, 14 and 21 by visual observations (number of emerged seedlings and phytotoxic effects) and on day 21 by shoot fresh weight and shoot height determination. The inhibition of shoot height, shoot fresh weight and rate of emergence was calculated in relation to the solvent control. Phytotoxic effects for the endpoint seedling emergence were observed only for the plant species rape at concentrations ≥ 320mg/kg, for plant species soybean no effects were observed up to and including the highest test concentration of 1000 mg/kg soil dw.
EC50 (21d) seedlings emergence > 1000 mg/kg for all tested plant species
NOEC (21d) seedlings emergence = 1000 mg/kg for oats and soybean
NOEC (21d) seedlings emergence >= 320 mg/kg for rape
Lowest effect concentrations recorded for phytotoxic effects regarding biomass were:
EC50 (21d) shoot fresh weight = 139 mg/kg for oats
NOECD (21d) shoot fresh weight = 32 mg/kg for oats
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.