Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 807-318-6 | CAS number: 22428-87-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Description of first aid measures
General advice:
Move out of dangerous area.
Show this safety data sheet to the doctor in attendance.
Do not leave the victim unattended.
Protection of first-aiders:
No action shall be taken involving any personal risk or without suitable training.
If inhaled:
If unconscious, place in recovery position and seek medical advice.
In case of skin contact:
Wash off with soap and plenty of water.
If symptoms persist, call a physician.
In case of eye contact:
Immediately flush eye(s) with plenty of water.
Remove contact lenses.
Protect unharmed eye.
Keep eye wide open while rinsing.
If eye irritation persists, consult a specialist.
If swallowed:
Keep respiratory tract clear.
Never give anything by mouth to an unconscious person.
Take victim immediately to hospital.
Most important symptoms and effects, both acute and delayed
Risks:
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Suspected of damaging the unborn child.
Indication of any immediate medical attention and special treatment needed
Treatment:
Treat symptomatically.
Fire-fighting measures
Extinguishing media
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or car-bon dioxide.
Unsuitable extinguishing media:
None known.
Special hazards arising from the substance or mixture
Specific hazards during fire-fighting:
Do not allow run-off from fire fighting to enter drains or water courses.
Hazardous combustion products:
Carbon dioxide (CO2)
Carbon monoxide
Advice for firefighters
Special protective equipment for firefighters:
Wear self-contained breathing apparatus for firefighting if nec-essary.
Further information:
Collect contaminated fire extinguishing water separately. This must not be discharged into drains.
Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal precautions:
Use personal protective equipment.
Environmental precautions:
Prevent product from entering drains.
Prevent further leakage or spillage if safe to do so.
If the product contaminates rivers and lakes or drains inform respective authorities.
Methods and material for containment and cleaning up
Methods for cleaning up:
Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust).
Keep in suitable, closed containers for disposal.
Handling and storage
Precautions for safe handling
Advice on safe handling:
Avoid formation of aerosol.
Do not breathe vapours/dust.
Avoid contact with skin and eyes.
Do not smoke.
Provide sufficient air exchange and/or exhaust in work rooms.
Dispose of rinse water in accordance with local and national regulations.
Smoking, eating and drinking should be prohibited in the ap-plication area.
Advice on protection against fire and explosion:
Normal measures for preventive fire protection.
Hygiene measures:
General industrial hygiene practice.
When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday.
Conditions for safe storage, including any incompatibilities
Requirements for storage areas and containers:
Keep container tightly closed in a dry and well-ventilated place. Observe label precautions. Electrical installations / working materials must comply with the technological safety standards.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Further information on storage stability:
Stable under recommended storage conditions.
Specific use(s):
No data available
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Control parameters
Occupational Exposure Limits
Components | CAS-No. | Value type (Form of exposure) | Control parameters | Basis |
toluene | 108-88-3 | TWA | 50 ppm 192 mg/m3 | 2006/15/EC |
Further information | Indicative, Identifies the possibility of significant uptake through the skin | |||
STEL | 100 ppm 384 mg/m3 | 2006/15/EC | ||
Further information | Indicative, Identifies the possibility of significant uptake through the skin | |||
TWA | 50 ppm 191 mg/m3 | GB EH40 | ||
Further information | Can be absorbed through the skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity. | |||
STEL | 100 ppm 384 mg/m3 | GB EH40 | ||
Further information | Can be absorbed through the skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity. |
Derived No Effect Level (DNEL) according to Regulation (EC) No. 1907/2006:
Substance name | End Use | Exposure routes | Potential health effects | Value |
toluene | Workers | Inhalation | Long-term exposure, Systemic effects | 192 mg/m3 |
Workers | Inhalation | Short-term exposure, Systemic effects | 384 mg/m3 | |
Workers | Inhalation | Long-term exposure, Systemic effects | 192 mg/m3 | |
Workers | Inhalation | Short-term exposure, Systemic effects | 384 mg/m3 | |
Workers | Dermal | Long-term exposure, Systemic effects | 384 mg/kg bw/day | |
Consumers | Inhalation | Long-term exposure, Systemic effects | 56.5 mg/m3 | |
Consumers | Inhalation | Short-term exposure, Systemic effects | 226 mg/m3 | |
Consumers | Inhalation | Long-term exposure, Systemic effects | 56.5 mg/m3 | |
Consumers | Inhalation | Short-term exposure, Systemic effects | 226 mg/m3 | |
Consumers | Dermal | Long-term exposure, Systemic effects | 226 mg/kg bw/day | |
Consumers | Oral | Long-term exposure, Systemic effects | 8.13 mg/kg bw/day |
Predicted No Effect Concentration (PNEC) according to Regulation (EC) No. 1907/2006:
Substance name | Environmental Compartment | Value |
toluene | Fresh water | 0.68 mg/l |
Freshwater - intermittent | 0.68 mg/l | |
Marine water | 0.68 mg/l | |
Sewage treatment plant | 13.61 mg/l | |
Fresh water sediment | 16.39 mg/kg dry weight (d.w.) | |
Marine sediment | 16.39 mg/kg dry weight (d.w.) | |
Soil | 2.89 mg/kg dry weight (d.w.) |
Exposure controls
Engineering measures
If user operations generate dust, fumes, gas, vapour or mist, use process enclosures, local ex-haust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits.
Personal protective equipment
Eye protection:
Tightly fitting safety goggles
Wear face-shield and protective suit for abnormal processing problems.
Hand protection
Wearing time:
< 60 min
Material:
Butyl rubber - IIR
Material:
Nitrile rubber - NBR
Remarks:
After contamination with product change the gloves immedi-ately and dispose of them according to relevant national and local regulations The suitability for a specific workplace should be discussed with the producers of the protective gloves.
Skin and body protection:
Impervious clothing
Choose body protection according to the amount and con-centration of the dangerous substance at the work place.
Respiratory protection:
In the case of vapour formation use a respirator with an ap-proved filter.
Vapour respirator
Filter type:
ABEK-filter
Stability and reactivity
Reactivity
No specific test data related to reactivity available for this product or its ingredients.
Chemical stability
Stable under normal conditions.
Possibility of hazardous reactions
Hazardous reactions:
Under normal conditions of storage and use, hazardous reac-tions will not occur.
Conditions to avoid
Direct sources of heat.
Incompatible materials
Materials to avoid:
Strong oxidizing agents
Hazardous decomposition products
Carbon monoxide Carbon dioxide (CO2)
Disposal considerations
Waste treatment methods
Product:
Do not contaminate ponds, waterways or ditches with chemi-cal or used container.
The product should not be allowed to enter drains, water courses or the soil.
Send to a licensed waste management company.
Contaminated packaging:
Empty remaining contents.
Dispose of as unused product.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.