Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-298-9 | CAS number: 82097-50-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to other aquatic organisms
Administrative data
- Endpoint:
- toxicity to other aquatic vertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- from October 13 2014 to October 27 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: US EPA 850.1025
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-(2-chloroethoxy)-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzene-1-sulfonamide
- EC Number:
- 617-298-9
- Cas Number:
- 82097-50-5
- Molecular formula:
- C14H16ClN5O5S
- IUPAC Name:
- 2-(2-chloroethoxy)-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]benzene-1-sulfonamide
- Test material form:
- solid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Water sample collected from each test chamber of each treatment and control group two days prior to the start of the exposure after conditioning the diluter for approximately one day. Water samples also were collected from each test chamber in each treatment and the control group at the beginning of the test and at 48 and 96 hours (± 1 hour) to measure concentrations of the test substance. An additional sample set was also taken at the beginning of the test and at 48 hours for possible analysis if confirmation of measured concentrations was required. The samples were collected from mid-depth, placed in glass vials, and processed immediately for analysis or stored under refrigeration for possible future analysis.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- A primary stock solution was prepared daily during the pre-exposure and exposure at a nominal concentration of 800 mg/L and proportionally delivered to each of the test concentrations during the test.
The stock was injected into the diluter mixing chambers assigned to treatment groups at target rates of 2.756, 5.688, 10.938, 21.875, and 43.750 mL/minute respectively, where they were mixed with dilution water delivered at rates of 332, 329, 326, 321, 310 and 288 mL/minute and algal feed suspension delivered at a rate of 18 mL/minute to achieve the desired test concentrations. The negative control received dilution water and algal feed suspension only at a combined rate of 350 mL/min.
Test organisms
- Aquatic vertebrate type (other than fish):
- other: Oyster
- Test organisms (species):
- other: Crassostrea virginica
- Details on test organisms:
- - from Marinetics, Inc., Cambridge, Maryland
- received 10 days prior to exposure initiation and were held in filtered saltwater from the same source as used during the test.
Study design
- Test type:
- flow-through
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 20±2℃
- Dissolved oxygen:
- 4.8 mg/L
- Salinity:
- 20‰
- Nominal and measured concentrations:
- Nominal: negative control, 6.3, 13, 25, 50, 100 mg/L
Measured: 5.9± 0.190, 13± 0.265, 24± 0.854, 53± 1.15, 100± 1.59 mg/L - Details on test conditions:
- Fluorescent light bulbs that emit wavelengths similar to natural sunlight were controlled by an automatic timer to provide a photoperiod of 16 hours of light and 8 hours of darkness. A 30-minute transition period of low light intensity was provided.
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: inhibition of shell growth
- Details on results:
- The test solutions in the mixing chambers and test chambers appeared clear and colorless at exposure initiation and clear and green due to algae feed at test termination, with no evidence of precipitation observed in any control or treatment solutions. Measured concentrations of the samples ranged from approximately 85 to 100% of nominal.
Percent inhibition of shell growth was calculated relative to the negative control data. Inhibition of shell growth in the 5.9, 13, 24, 53 and 100 mg/L treatment groups was 22, 20, 9, 14 and 24%, respectively
Applicant's summary and conclusion
- Conclusions:
- No concentration resulted in >50% inhibition of shell growth, the 96-hour EC50 was empirically estimated to be >100 mg/L, the highest concentration tested. The NOEC was determined to be 100 mg/L.
- Executive summary:
Eastern oysters (Crassostrea virginica) were exposed for 96 hours under flow-through conditions to five concentrations of triasulfuron TGAI ranging from 5.9 to 100 mg/L. The 96-hour EC50 value was greater than 100 mg/L, the highest concentration tested. The NOEC was determined to be 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.