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EC number: 856-079-4 | CAS number: 55860-35-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- gas saturation method
Test material
- Reference substance name:
- 4-acetyl-2-methylbenzoic acid
- EC Number:
- 856-079-4
- Cas Number:
- 55860-35-0
- Molecular formula:
- C10H10O3
- IUPAC Name:
- 4-acetyl-2-methylbenzoic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Vapour pressure
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
Transition / decomposition
- Key result
- Transition / decomposition:
- no
Any other information on results incl. tables
The recovery of test substance at two levels was 103.3 and 101.0%.
The results of the experiments are summarised in the following table:
Test temperature (°C) | Volume N2 (m3) | Amount collected (µg) in first trap | Amount collected (µg) in second trap | Total amount collected (µg) | Vapour pressure (mPa) |
30.0 | 27.94 | 0.366 | - | 0.366 | 0.059 |
30.0 | 36.95 | 0.503 | - | 0.503 | 0.061 |
30.0 | 47.77 | 0.687 | - | 0.687 | 0.065 |
40.0 | 27.04 | 0.470 | - | 0.470 | 0.179 |
40.0 | 35.76 | 0.603 | - | 0.603 | 0.174 |
40.0 | 46.23 | 0.982 | - | 0.982 | 0.219 |
50.0 | 26.20 | 0.354 | - | 0.354 | 0.571 |
50.0 | 35.50 | 0.472 | - | 0.472 | 0.563 |
50.0 | 44.80 | 0.665 | - | 0.665 | 0.628 |
Applicant's summary and conclusion
- Conclusions:
- The vapour pressure of the substance, as determined by the gas saturation method, has been determined to be 0.018 mPa at 20 °C.
- Executive summary:
The vapour pressure of the substance was studied under GLP to OECD TG 104 (2006) using the gas saturation method. Saturator columns were filled with glass beads loaded with the test substance and conditioned and thermostated at the test temperature for a sufficient time to remove any higher volatile impurities by passing through a supply of dry nitrogen. The gas flows were set by mass flow controllers and the gas was passed over the samples fro the appropriate collecting time. Two condensation tubes were connected in series to the outlet of each of the three saturator columns. The condensation tubes were placed in a cooling trap at a temperature of 2.0 °C in cryobath. The transported test item was condensated at this temperature. After completing the test the condensation tubes were disconnected from the saturator columns and the amount of transferred test item in each of the condensation tubes was determined using an analytical method (HPLC with external standard), for which accuracy (with regards to linearity, recovery, specificity and precision) was demonstrated. A comparison of the retention times of the the substance in the reference solutions and the sample solutions showed that the identity of the test substance had not altered during the experiment. All tests were performed at 30, 40 and 50 °C. To ensure saturation control, three different flow rates were chosen at each of the test temperatures. At all three test temperatures, the flow rate was in the range from 26.2 to 47.77 mL/minute. The vapour pressure of the substance was calculated from the total amounts collected in the traps, and has been determined as 0.018 mPa at 20 °C and 0.034 mPa at 25 °C.
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