Registration Dossier
Registration Dossier
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EC number: 292-124-9 | CAS number: 90552-04-8
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
LOEC (21d): > 10 mg/L
NOEC (21d): ≥ 10 mg/L
Key value for chemical safety assessment
Additional information
In a 21-day chronic toxicity study, Daphnia magna were exposed to 2-Propenoic acid, 2-methyl-, C13-15-branched and linear alkyl esters to loading rates of 0 (control) and 10 mg/L under semi-static, daily renewal conditions in accordance with the OECD 211 guideline. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. Mortality, reproduction and sublethal effects were observed daily.
The 21-day effect concentrations for 2-Propenoic acid, 2-methyl-, C13-15-branched and linear alkyl esters in Daphnia magna were:
LOEC > 10 mg/L
NOEC ≥ 10 mg/L
The overall effect concentrations (mg/L) are based on reproduction (living offspring per surviving adult) as the primary population relevant response and were obtained based on loading rate. The test substance did not have a chronic toxic effect on Daphnia magna up to a loading rate of 10 mg/L. No significant mortality or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments. The data were not sufficient to calculate ECx values for reproduction or growth, since the study is designed as a limit test. The concentration of test substance in test media could not be verified analytically, therefore the effect concentrations are based on the loading rate used to prepare the test substance WAF solutions. According to guidance in OECD 23, for tests with chemicals that cannot be quantified by analytical methods at the concentrations causing effects, the effect concentration can be expressed based on the nominal concentrations or in the case of water accommodated fractions on the loading rate. The toxicity results presented here are consistent with the results from preliminary tests. The results in this study are consistent with all validity criteria and the test is valid according to the guidelines of this study. No deviations from test guidelines or other incidents occurred during the course of the reported test which may have influenced the results.
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