p-nitrophenyl dihydrogen phosphate, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:2)

Auto flammability

Administrative data

Endpoint:

relative self-ignition temperature (solids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

See further information in the cross-ref.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

16-17 November 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: The Grewer Oven test (VDI guideline 2263, part l , l990, Test methods for the Determination o f the Safety Characteristics of Dusts)

Deviations:

no

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

Batch No.: 46587100
Storage: Refrigerator (approx. 2-8°C)

Key result

Test procedure:

other: screening test for self-ignition in the Grewer-Oven with pure test item

Max. temp. reached:

412

Result:

other: An endothermic effect could be observed starting at a temperature of 140 °C. No further thermal effects could be observed up to the maximum test temperature of 412 °C.

Remarks on result:

other: A black residue remained in the wire basket after the test

Key result

Test procedure:

other: screening test for self-ignition in the Grewer-Oven (test item in mixture with Kieselguhr)

Max. temp. reached:

335

Result:

other: A small exothermic effect was detected starting at approx. 190 °C which led to a temperature increase up to 335 °C (corresponding temperature of the reference material 317 °C).

Remarks on result:

other: Before the small exothermic effect, an endothermic effect could be observed starting at a temperature of 140 °C. A black/grey residue remained in the wire basket after the test.

In the investigation of self-ignition in the Grewer Oven for the pure test item an endothermic effect could be observed starting at a temperature of 140 °C. No further thermal effects could be observed up to the maximum test temperature of 412 °C. A black residue remained in the wire basket after the test.

For the test item in mixture with Kieselguhr an endothermic effect could be observed starting at a temperature of 140 °C. A small exothermic effect was detected starting at approx. 190 °C which led to a temperature increase up to 335 °C (corresponding temperature of the reference material 317 °C). A black/grey residue remained in the wire basket after the test.

The table below shows the results of the screening test.

Experiment	Onset self- ignition / °C	Maximum temperature / °C
Pure test item	---	---
Test item in mixture with Kieselguhr (1:1)	approx. 190	335

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The pure test item 4-NPP, di-TRIS (CAS no. 68189-42-4) showed an endothermic effect starting at a temperature of 140 °C. No further thermal effects could be observed up to the maximum test temperature of 412 °C.
On the basis to the results of the tests on the self-ignition in the Grewer Oven the test item is classified as follows:
UN Transport Regulation: The test item does not have to be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No. 1272/2008 Annex I: 2.11: The test item does not have to be classified as self-heating substance according to GHS / CLP Regulation (EC) No. 1272/2008 Annex I: 2.11.

Executive summary:

The pure test item 4-NPP, di-TRIS (CAS no. 68189-42-4) showed an endothermic effect starting at a temperature of 140 °C. No further thermal effects could be observed up to the maximum test temperature of 412 °C.
On the basis to the results of the tests on the self-ignition in the Grewer Oven the test item is classified as follows:
UN Transport Regulation: The test item does not have to be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No. 1272/2008 Annex I: 2.11: The test item does not have to be classified as self-heating substance according to GHS / CLP Regulation (EC) No. 1272/2008 Annex I: 2.11.