Registration Dossier
Registration Dossier
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EC number: 203-613-3 | CAS number: 108-75-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- not indicated
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Pyridine and Pyridine Derivatives
- Author:
- Shimizu, S., Watanabe, N., Kataoka, T., Shoji, T., Abe, N., Morishita, S., Ichimura, H.
- Year:
- 2 012
- Bibliographic source:
- Ullmann's Encyclopedia of industrial chemicals, 2012, Wiley-VCH Verlag, DOI: 10.1002/14356007.a22_399
Materials and methods
Test guideline
- Guideline:
- other: no Guideline reported
- GLP compliance:
- not specified
- Remarks:
- Data from handbook, experimental data generated before 2008
Test material
- Reference substance name:
- 2,4,6-trimethylpyridine
- EC Number:
- 203-613-3
- EC Name:
- 2,4,6-trimethylpyridine
- Cas Number:
- 108-75-8
- Molecular formula:
- C8H11N
- IUPAC Name:
- 2,4,6-trimethylpyridine
- Test material form:
- not specified
- Details on test material:
- handbook/data collection/publication
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 400 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- The LD50 in rats of the test item was found to be 400 mg/kg bw.
- Executive summary:
The LD50 in rats of the test item was found to be 400 mg/kg bw.
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