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EC number: 700-363-1 | CAS number: 1335203-20-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Principles of method if other than guideline:
- The sample was prepared in triplicate in solid saturator columns between glass wool plugs. The columns were placed into the custom built thermostated incubator (set at 25°C) and attached to the Nitrogen gas line. One end of each of the columns ¿poked¿ out of the side of the incubator, where an adequately sized vessel was securely attached to act as a trap for the analyte. The analyte was trapped in 2-Propanol. The gas flow rate was directly measured (in triplicate) periodically throughout the analysis.
After a finite length of time, all the traps were quantitatively transferred to individual 100ml volumetric flasks. All solutions were filled to the mark with 2-Propanol when equilibrated to RT. All solutions (the solutions were called VP 1, VP 2 and VP 3 respectively) were analysed by GC-FID to quantitate any analyte present - GLP compliance:
- yes
- Type of method:
- gas saturation method
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- < 0.002 Pa
- Conclusions:
- Vapour pressure at 24.4°C for the specified analyte = <2.5x10-3Pa (and inferred at 20°C = <2.5x10-3Pa ).
- Executive summary:
The above data doesn't prove, definitively, that gas saturation had occurred (as no analyte was detected and as a consequence all subsequent calculations were carried out using a ¿less than figure¿ than the LOQ) and therefore it has been assumed. For gas saturation to be achieved, the extreme gas flow rates (VP 1 versus VP 3) have to be >30% different (which they were for this analysis, 96.7% difference in extreme gas flow rate) and the calculated vapour pressure be <30% different.
As a result, the worst case scenario has been quoted as the result (VP1 data), purely as it gave the largest, calculated vapour pressure data (due to it having the slowest gas flow rate).
In conclusion, on the assumption that these gas flow rates would have achieved gas saturation of the analyte and that the analyte was stable in solution for the duration of the analysis, ASG:10423936 vapour pressure at 24.4°C for the specified analyte = <2.5x10-3Pa (and inferred at 20°C = <2.5x10-3Pa ).
Reference
The above data doesn't prove, definitively, that gas saturation had occurred (as no analyte was detected and as a consequence all subsequent calculations were carried out using a ¿less than figure¿ than the LOQ) and therefore it has been assumed. For gas saturation to be achieved, the extreme gas flow rates (VP 1 versus VP 3) have to be >30% different (which they were for this analysis, 96.7% difference in extreme gas flow rate) and the calculated vapour pressure be <30% different.
As a result, the worst case scenario has been quoted as the result (VP1 data), purely as it gave the largest, calculated vapour pressure data (due to it having the slowest gas flow rate).
In conclusion, on the assumption that these gas flow rates would have achieved gas saturation of the analyte and that the analyte was stable in solution for the duration of the analysis, ASG:10423936 vapour pressure at 24.4°C for the customer specified analyte = <2.5x10-3Pa (and inferred at 20°C = <2.5x10-3Pa ).
Description of key information
The vapour pressure of the test material was determined according to test guideline EU A4
Key value for chemical safety assessment
- Vapour pressure:
- 0.003 Pa
- at the temperature of:
- 20 °C
Additional information
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