Reaction products of cyclohexylamine and 4-alkylaniline and 1,1'-methanediylbis(4-isocyanatobenzene)

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 1996-01-04 to 1996-05-09

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

GLP study in accordance with recognised test guideline but: Lot/batch No.: not stated Expiration date of the lot/batch: not stated Storage condition of test material: not stated NOTE: study deemed acceptable because spectral data for A-3622 are available, covering before and after the test period - see section 1.4 Analytical Information.

Qualifier:

according to guideline

Guideline:

other: BS 3406, Part 4 (1993)

Deviations:

no

GLP compliance:

yes

Type of method:

microscopic examination

Type of particle tested:

primary particle

Type of distribution:

other: mass distribution

Specific details on test material used for the study:

- Substance type: Organic
- Physical state: Solid
- Composition of test material, percentage of components: relative proportions components 1, 2 and 3 are 100:60:40

Percentile:

other: 11.3% by mass

Mean:

< 10 µm

Remarks on result:

other: Standard deviation not determined

Six replicate tests were performed, samples for each being taken individually from the original bulk container of test item. The results can be summarised as follows:

Particle size (μm)	% mass
	Test 1	Test 2	Test 3	Test 4	Test 5	Test 6	Mean
>125 (sieved)>105 60.0 -105 30.0 – 60.0 10.4 – 30.0 0.5 – 10.4	51.0 0.0 10.8 25.0 10.8 2.4	52.1 0.0 0.0 9.5 23.8 14.6	52.3 0.0 0.0 24.9 15.9 6.9	51.4 0.0 2.0 13.7 20.8 12.1	52.1 0.0 0.0 10.1 21.7 16.0	53.8 0.0 0.0 10.0 20.4 15.8	52.1 0.0 2.1 15.5 18.9 11.3

The results indicate that 11.3% by mass of tets item is smaller than 10 µm.

Conclusions:

The results indicate that 11.3% by mass of test item is smaller than 10 µm.

Executive summary:

The granulometry was determined based on BS 3406, Part4 (1993).

A preliminary test was conducted using sieve analysis, 10% by weight of the test material was found to be of particle size <75 microns, image analysis was subsequently performed. Six replicate tests were performed, samples for each being taken individually from the original bulk container of test item. 11.3% by mass of test item is smaller than 10 µm.

Description of key information

Particle size was determined in accordance with BS 3406 Part 4 (1993) following a preliminary determination using sieve analysis. Six replicate tests were performed, samples for each being taken individually from the original bulk container of test item. 11.3% by mass of test item is smaller than 10 µm.