2-(4-Bromphenyl)-5-butyl-1,3-dioxane, trans-

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-12-04 to 2018-02-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 40 - <= 70 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Sublimation:

no

Melting point / melting range: DSC measurement

Three DSC measurements with a heating rate of 10 K/min showed a double-stage endothermal effect (melting) in the temperature range of 40 -70 °C.

The results of the DSC measurements are summarized in Table 1.

 

Table 1: Melting point (DSC measurements)

Ident No.	Test item / mg	Starting temperature/ °C	Final test temperature / °C	Temperature range (endo- thermal) / °C	Onset (melting) / °C	Crucible	Observations after the measurement
34723	14.09	25	1 500	40-65	double- stage	Aluminium with a hole
34724	16.81	25	100	45 - 65	double- stage	Aluminium with a hole	Test item was a melt no mass loss
34725	16.74	25	400	40 - 70	double- stage	Aluminium with a hole

 

Because of the double-stage effect, the melting of the test item was given in a range. The test item had a melting range of 40 - 70 °C.

Conclusions:

The melting range of the substance was determined to be between 40 and 70 °C at 1013.25 hPa.

Executive summary:

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 14 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. The test item was heated up from the starting temperature (0 °C) to the final temperature (500 °C) at a constant heating rate (10 K/min) in a defined atmosphere (nitrogen). Two DSC-measurements showed two endothermic effects in the temperature range of 40 - 70 °. Because of the double-stage effect, the melting of the test item was given in a range. The test item had a melting range of 40 - 70 °C.

Description of key information

The melting range of the substance was determined to be between 40 and 70 °C at 1013.25 hPa.

Additional information

A study was conducted according to OECD test guideline 102, Regulation (EC) No 440/2008 method A.1 and EPA OCSPP test guideline 830.7200 to determine the melting point of the test item using differential scanning calorimetry (reference 4.2 -1). The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with about 14 – 16 mg of the test item were performed. As reference crucible, an empty aluminium crucible was used. The substance is a solid at ambient conditions. The test item was heated up from the starting temperature (0 °C) to the final temperature (500 °C) at a constant heating rate (10 K/min) in a defined atmosphere (nitrogen). Two DSC-measurements showed two endothermic effects in the temperature range of 40 - 70 °. Because of the double-stage effect, the melting of the test item was given in a range. The test item had a melting range of 40 - 70 °C.