Pentaerythritol tetrabenzoate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08.04.2019 - 11.04.2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Specific details on test material used for the study:

Name: Pentaerythritol tetrabenzoate
Appearance: off-white solid
Composition: Pentaerythritol tetrabenzoate >96%
CAS No.: 4196-86-5
EINECS-No.: 224-079-8
Molecular formula: C33H28O8
Molecular weight: 552.576 g/mol
Purity: >96%
Homogeneity: homogeneous
Expiry date: Nov. 2018
Storage: Room Temperature (20 ± 5°C)

Key result

Water solubility:

< 10 µg/L

Conc. based on:

test mat.

Incubation duration:

ca. 1 h

Temp.:

20 °C

pH:

>= 4.2 - <= 5.1

Details on results:

At flow rate 1 (25 mL/h) six consecutive samples, and at flow rate 2 (12.5 mL/h) five con-secutive samples were analysed and no signals were detected.

For all fractions no Tyndall effect (i.e. a laser beam was not scattered when transmitted through the liquid) could be observed indicating that no colloidal dispersed particles or mi-celles was present.

No signals were detected, at all collected samples at each flow rates.
Therefore, the solubility of Pentaerythritol tetrabenzoate in water lay below the limit of quantification (10 µg/L) and is stated as
< 10 µg/L units at 20 °C
< 1.0*10-5 kg/m3 (SI units)

Conclusions:

The solubility of Pentaerythritol tetrabenzoate in water lay below the limit of quantification (10 µg/L) and is stated as
< 10 µg/L units at 20 °C
< 1.0*10-5 kg/m3 (SI units)

Executive summary:

The solubility of Pentaerythritol tetrabenzoate in demineralised water was determined us-ing the column elution method following OECD 106.

No signals were detected, at all collected samples at each flow rates.

Therefore, the solubility of Pentaerythritol tetrabenzoate in water lay below the limit of quantification (10 µg/L) and is stated as

< 10 µg/L units at 20 °C

< 1.0*10-5 kg/m3 (SI units)

For all fractions no Tyndall effect (i.e. a laser beam was not scattered when transmitted through the liquid) could be observed indicating that no colloidal dispersed particles or mi-celles was present.

The measured pH value of the fractions in both flow rates were in the range of 4.2 – 5.1

No observations arousing doubts concerning the accuracy of the results and the validity of the study were made.

Description of key information

The solubility of Pentaerythritol tetrabenzoate in demineralised water was determined us-ing the column elution method following OECD 106.

No signals were detected, at all collected samples at each flow rates.

Therefore, the solubility of Pentaerythritol tetrabenzoate in water lay below the limit of quantification (10 µg/L) and is stated as

< 10 µg/L units at 20 °C

< 1.0*10-5 kg/m3 (SI units)

For all fractions no Tyndall effect (i.e. a laser beam was not scattered when transmitted through the liquid) could be observed indicating that no colloidal dispersed particles or mi-celles was present.

The measured pH value of the fractions in both flow rates were in the range of 4.2 – 5.1

No observations arousing doubts concerning the accuracy of the results and the validity of the study were made.

Key value for chemical safety assessment

Water solubility:

10 µg/L

at the temperature of:

20 °C