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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17.12.1996 - 18.02.1997
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentatriacontan-18-one
EC Number:
207-993-1
EC Name:
Pentatriacontan-18-one
Cas Number:
504-53-0
Molecular formula:
C35H70O
IUPAC Name:
pentatriacontan-18-one
Test material form:
solid
Specific details on test material used for the study:
Purity : 84.1 % (by GC), - Impurities (identity and concentrations) : Heptadecyl pentadecyl ketone (HPK) : 13.7 % (by GC), Heptadecyl hexadecyl ketone (HHK) % (by GC), - Identification of each peak for test material and impurity : Peak 1 : Heptadecyl pentadecyl ketone (HPK), Peak 2 : 18-Pentatriacontanone
Radiolabelling:
not specified

Sampling and analysis

Details on sampling:
- Nominal concentrations
1st Concentration area : 1 mg/L,
2nd Concentration area : 0.1 mg/L

Test solutions

Vehicle:
yes
Details on preparation of test solutions, spiked fish food or sediment:
PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances) - Chemical name of vehicle: Crystal sugar, HCOvehicle:
1st Concentration area: Crystal sugar 30 mg/L, HCO-40 20 mg/L, 2nd Concentration area: Crystal sugar 3 mg/L, HCO-40 2 mg/L
Recovery ratio : Test water : Peak 1 87.1 %, Peak 2 97.4 %, Fish : Peak 1 86.5 %, Peak 2 83.8 %, - Limit of quantitation : Test water : 1st concentration area : 1 0.043 mg/L, Peak 2 0.041 mg/L, 2nd concentration area : Peak 1 0.0043 mg/L, Peak 2 0.0041 mg/L, Fish : Peak 1 1.9 microg/g, Peak 2 2.1

Test organisms

Test organisms (species):
Cyprinus carpio

Study design

Route of exposure:
aqueous
Justification for method:
other: not specified
Test type:
not specified
Water / sediment media type:
not specified
Total exposure / uptake duration:
6 wk

Test conditions

Details on test conditions:
RANGE-FINDING / PRELIMINARY STUDY - Test concentrations : LC50(48h) >= 130 mg/L, Rice fish(Oryzias latipes)
Nominal and measured concentrations:
- Nominal concentrations 1st Concentration area : 1 mg/L, 2nd Concentration area : 0.1 mg/L
Reference substance (positive control):
not specified

Results and discussion

Lipid content
Lipid content:
4.3
Time point:
start of exposure
Bioaccumulation factoropen allclose all
Conc. / dose:
0.899 mg/L
Type:
BCF
Value:
<= 2.4 L/kg
Basis:
not specified
Remarks:
test material
Conc. / dose:
0.092 mg/L
Type:
BCF
Value:
<= 23 L/kg
Basis:
not specified
Remarks:
test material

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
In a Bioaccumulation test of a chemical substance in fish with stearone BCF-values of up to 23 have been determined, which is far below the screening criteria according to annex XII of REACH. Based on this stearone is considered a substance with a low potential to bioaccumulate in organisms.