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EC number: 269-824-8 | CAS number: 68334-33-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Early 1980's
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Results published in a scientific review. and peer reviewed in the European RAR.
- Justification for type of information:
- The primary component of all substances provide complete coverage of 68334-33-8. 68334-33-8 shares high structural similarity with 61789-80-8, 68783-78-8, 107-64-2, and 112-02-7. As 68334-33-8 is a UVCB its components encapsulate the other substances except for the counter ion (Cl-). In solution, the counter ions will dissociate from the parent structures. Therefore, we are comparing substances of equivalent nature. CAS 107-64-2 represents the C18 boundary of the 61789-80-8. Ignoring the salt component CAS 61789-80-8 is equivalent to CAS 68334-33-8. 68783-78-8 is a worst case of both 68334-33-8 and 61789-80-8 since it is unsaturated and the SP2 carbon-carbon bonds are of higher reactivity and a more likely site of metabolic activation. The primary component of CAS 112-02-7 is a substructure of all the other substances. Additional documentation, provided within the IUCLID Assessment Reports section, supports the read-across approach.
- Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- other: U.S. Environmental Protection Agency. 1975. Methods for acute toxicity tests with fish, macro invertebrates and amphibians. Ecological Research Service EPA-660/3-75-009.
- GLP compliance:
- no
- Vehicle:
- yes
- Details on test solutions:
- The test materials, because of their low solubility in water and their high adsorption characteristics, were typically added to the test water with either ethanol or isopropanol to maximize dispersion and availability to the test species. Whenever a solvent was used, a solvent control containing the highest amount of solvent in the test was also included, but at no time did the concentration of solvent exceed recommended limits.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnids used in the 48-h static toxicity test (< 24 h old) were obtained from culture units at the respective test laboratories.
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 345-363 (White river)
131-163 (Reconstituted water) - Test temperature:
- 19-22°C
- pH:
- 8.4-8.6 (White river)
6.5-7.3 (Reconstituted water) - Dissolved oxygen:
- no data
- Details on test conditions:
- The toxicity tests were conducted in 250-ml glass beakers containing either 150 or 200 ml test solution. These waters were maintained at 19 to 22°C and were not aerated during testing. Mortality of the daphnids in each test chamber was recorded daily. The five test material concentrations, the control and, when appropriate, the solvent control were done in triplicate. The 48-h LC50 values and associated 95% CI were based on nominal levels of the active ingredient and were
calculated using the same statistical methods as those used to analyze bluegill mortality. - Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.16 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- in reconstituted water
- Basis for effect:
- mortality
- Remarks on result:
- other: (pH 6.5-7.3, CaCO3 131-163 mg/L, no suspended solids)
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- in river water
- Basis for effect:
- mortality
- Remarks on result:
- other: Water from White river: pH 8.4-8.6, CaCO3 345-363 mg/L, 3-5 mg/L susp. solids)
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The acute toxicity of DSDMAC to Daphnia has been tested in river and reconstituted water. The LC50 (48h) was 3.1 mg/L (river water) and 0.16 mg/L (reconstituted water) in operational conditions.
- Executive summary:
Acute toxicity to daphnids varied with the type of dilution water used in the toxicity tests. In laboratory dilution water, the 48-h LC50 values for DSDMAC was 0.16 mg/L. However, in river water, acute toxicity
was considerably less, with a 48-h EC50 of 3.1 mg/L.
Reference
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.16 mg/L
Additional information
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