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EC number: 239-996-9 | CAS number: 15872-89-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Diheptyl succinate
- EC Number:
- 239-996-9
- EC Name:
- Diheptyl succinate
- Cas Number:
- 15872-89-6
- Molecular formula:
- C18H34O4
- IUPAC Name:
- 1,4-diheptyl butanedioate
- Test material form:
- liquid
- Details on test material:
- LOT# BH9326
CAS No. 15872-89-6
sample date: Aug/06/2012
Acid Value, mg KOH/g 0.10 Max.
Kinematic Visc.@25°C, cSt 7.0 to 9.0
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- DILUTION WATER: Fortified well water
pH: 8.1
Conductivity: 520 μS/cm
Total hardness as CaCO3: 160 mg/L
Total alkalinity as CaCO3: 90 mg/L
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnia magna,
Age: < 24 hours old at exposure initiation
Source: Smithers Viscient culture facility
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Total hardness as CaCO3: 160 mg/L
- Test temperature:
- temperature range of 19 to 21 ºC
- pH:
- 8.1
- Salinity:
- Total alkalinity as CaCO3: 90 mg/L
- Conductivity:
- Conductivity: 520 μS/cm
- Nominal and measured concentrations:
- nominal test conc. 6.3, 13, 25, 50 and 100 mg/L
- Details on test conditions:
- 48-hour duration, temperature range of 19 to 21 ºC, photoperiod of 16 hours light and 8 hours darkness, light intensity range of 32 to 85 footcandles (340 to 910 lux)
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Based on nominal concentrations of diheptyl succinate, the 48−hour EC50 value was empirically estimated to be > 100 mg/L, the highest nominal concentration tested. The No-Observed-Effect Concentration (NOEC) was determined to be 100 mg/L. The highest concentration producing 0% immobilization was 100 mg/L. The lowest concentration producing 100% immobilization was > 100 mg/L.
Additional testing to further define the EC50 value was not performed since the highest nominal concentration tested (100 mg/L) represents the highest concentration required by the OECD testing guidelines.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Based on nominal concentrations of diheptyl succinate, the 48−hour EC50 value was empirically estimated to be > 100 mg/L, the highest nominal concentration tested. The No-Observed-Effect Concentration (NOEC) was determined to be 100 mg/L. The highest concentration producing 0% immobilization was 100 mg/L. The lowest concentration producing 100% immobilization was > 100 mg/L.
Additional testing to further define the EC50 value was not performed since the highest nominal concentration tested (100 mg/L) represents the highest concentration required by the OECD testing guidelines.
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