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EC number: 221-516-4 | CAS number: 3129-92-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 December 2002 to 13 December 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Justification for type of information:
- Reliable experimental study following OECD guidelines (not specified), ISO14669:1999 (E) and GLP standards.
- Qualifier:
- according to guideline
- Guideline:
- other: ISO14669:
- Version / remarks:
- 1999 (E)
- Deviations:
- not specified
- Principles of method if other than guideline:
- ISO14669:1999 (E) - Water Quality - Determination of Acute Lethal Toxicity to Marine Copepods (Copepoda, Crustacea).
- GLP compliance:
- yes
- Specific details on test material used for the study:
- The test substance is yclohexylamine benzoate. The test substance was obtained from the study Sponsor on 5th September 2002 and stored in the original container at 15 ± 2°C.
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Acartia tonsa – Marine copepod
- Details on test organisms:
- The test was carried out using Acartia tonsa (12 -15 days old) obtained from Guernsey Sea Farms, Guernsey.
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 20.0 °C to 20.0 °C
- pH:
- 7.22 to 8.11
- Dissolved oxygen:
- 84.7 %ASV to 97.0 %ASV
- Nominal and measured concentrations:
- An experimental study was conducted with test concentrations of 20.0, 35.6, 63.2, 112.4, 200.0 and 355.6 mg/L.
- Reference substance (positive control):
- yes
- Remarks:
- 3, 5- dicholorphenol
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 136.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 355.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Results with reference substance (positive control):
- Raw results with reference substance 3,5-dichlorophenol were reported, but the EC50 was not calculated.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The test substance did induce acute immobilisation of Acartia tonsa at the nominal test concentrations after 48 h of exposure. The 24- and 48-hour EC50 values were reported as >355.6 mg/L and 136.6 mg/L, respectively
Reference
Description of key information
The key study was a static acute invertebrate toxicity test on the effects of the substance on the marine copepod Acartia tonsa following the guideline ISO 14669:1999 (E). Acute immobilisation of Acartia tonsa was observed; the 48-h EC50 was reported as = 136.6 mg/L (nominal).
Key value for chemical safety assessment
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 136.6 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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