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Diss Factsheets
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EC number: 247-161-5 | CAS number: 25646-71-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Feb 2018 to 28 Mar 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The Department of Health of the Government of the United Kingdom
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 542.128 µm
- Geometric standard deviation:
- >= 2.03 - <= 2.077
- Percentile:
- D10
- Mean:
- 156.275 µm
- St. dev.:
- 4.308
- Percentile:
- D50
- Mean:
- 442.645 µm
- St. dev.:
- 7.751
- Percentile:
- D90
- Mean:
- 835.414 µm
- St. dev.:
- 16.35
Reference
Full Test Results
|
RUN1 |
RUN2 |
RUN3 |
RUN4 |
RUN5 |
Average** |
Volume weighted mean |
481.172 |
476.077 |
460.788 |
468.169 |
485.309 |
474.303 |
Median |
450.131 |
444.102 |
429.932 |
438.717 |
450.719 |
442.645 |
Mode |
512.821 |
507.324 |
494.747 |
505.640 |
513.985 |
506.850 |
MMAD* |
551.296 |
543.911 |
526.557 |
537.316 |
522.016 |
542.128 |
d10(10% of material is<) |
161.912 |
157.704 |
150.567 |
152.321 |
159.567 |
156.275 |
d50(50% of material is<) |
450.131 |
444.102 |
429.932 |
438.717 |
450.719 |
442.645 |
d90(90% of material is<) |
843.609 |
838.978 |
812.708 |
822.288 |
859.267 |
835.414 |
All results are in µm
* Mass median aerodynamic diameter
** Average result is calculated from the entirety of data captured in each run and is not a simple arithmetic mean.
0.0 % by volume of sample was seen to be < 10.00 µm.
Standard Deviation results
RunNo. |
1 |
2 |
3 |
4 |
5 |
STDVP |
%STDVP |
d10(10%of material is<) |
161.912 |
157.704 |
150.567 |
152.321 |
159.567 |
4.308 |
2.8 |
d50(50%of material is<) |
450.131 |
444.102 |
429.932 |
438.717 |
450.719 |
7.751 |
1.8 |
d90(90%of material is<) |
843.609 |
838.978 |
812.708 |
822.288 |
859.267 |
16.350 |
2.0 |
d15.78(15.78%of material is<) |
221.780 |
216.259 |
207.013 |
211.215 |
218.705 |
5.280 |
2.5 |
GSD |
2.030 |
2.054 |
2.077 |
2.077 |
2.061 |
0.018 |
0.9 |
MMAD |
551.296 |
543.911 |
526.557 |
537.316 |
522.016 |
10.796 |
2.0 |
GSD = Geometric standard dev. of the lognormal particle size distribution (calculated from d50/d15.78)
STDVP = standard deviation of the population
% STDVP = percentage standard deviation of the population
Coefficient of variation for d50 is less than 3%; d10 and d90 are less than 5%. Thus repeatability of the characteristic particles in the size distribution are within the acceptable limits as per the ISO 13320-1 test standard.
Description of key information
d10 is 156.275 µm (ISO 13320, laser diffraction)
d50 is 442.645 µm (ISO 13320, laser diffraction)
d90 is 835.414 µm (ISO 13320, laser diffraction)
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.