(1-ethoxyethoxy)cyclododecane

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12-06-2001 to 12-07-2001

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study performed under GLP. All relevant validity criteria were met.

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

inspected: February 2000; signature: April 2000

Type of method:

effusion method: vapour pressure balance

Temp.:

25 °C

Vapour pressure:

0.204 Pa

Remarks on result:

other: Mean Vp (n=7): extrapolated from ln Vp (Pa) vs. 1/T curve of 7 individual runs

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

0.221 Pa

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.23 Pa

Test no.:

#3

Temp.:

25 °C

Vapour pressure:

0.226 Pa

Test no.:

#4

Temp.:

25 °C

Vapour pressure:

0.165 Pa

Test no.:

#5

Temp.:

25 °C

Vapour pressure:

0.203 Pa

Test no.:

#6

Temp.:

25 °C

Vapour pressure:

0.246 Pa

Test no.:

#7

Temp.:

25 °C

Vapour pressure:

0.135 Pa

Table 1.0 – vapour pressure determination of the test item

Run	Log10 Vp (25°C)	Vp(25°C) [Pa]
1	-0.656	0.221
2	-0.638	0.230
3	-0.645	0.226
4	-0.782	0.165
5	-0.693	0.203
6	-0.609	0.246
7	-0.871	0.135
Mean		0.204

 

The slop and intercept of the seven (7) individual runs for the plot of Log10 Vp (Pa) versus reciprocal of temperature (K) is recorded in the full study report.

There was no evidence of decomposition during the course of the test (no change in appearance).

Conclusions:

The vapour pressure of the test item has been determined to be 0.20 Pa at 25 °C.

Executive summary:

The vapour pressure was determined using EU Method A.4 guideline using the vapour pressure balance method under GLP. Measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. The temperature of the sample was controlled electronically. The mass and temperature readings were recorded automatically into a computer file. The difference in mass readings with the orifice covered and uncovered is proportional to the vapour pressure at the given oven temperature. Temperature and pressure readings were taken between 5 and 20°C with a one-hour dwell time at 5°C between runs. The vapour pressure of the test item was extrapolated from the vapour pressure curve (log10 Vp versus 1/T). The mean vapour pressure based on seven runs was 0.204 Pa at 25°C.

Description of key information

Vapour Pressure: 0.204 Pa at 25 °C, EU Method A.4 – vapour pressure balance method, 2002

Key value for chemical safety assessment

Vapour pressure:

0.204 Pa

at the temperature of:

25 °C

Additional information

Key study : EU Method A.4, 2002 : The vapour pressure was determined using EU Method A.4 guideline using the vapour pressure balance method under GLP. Measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. The temperature of the sample was controlled electronically. The mass and temperature readings were recorded automatically into a computer file. The difference in mass readings with the orifice covered and uncovered is proportional to the vapour pressure at the given oven temperature. Temperature and pressure readings were taken between 5 and 20°C with a one-hour dwell time at 5°C between runs. The vapour pressure of the test item was extrapolated from the vapour pressure curve (log10 Vp versus 1/T). The mean vapour pressure based on seven runs was 0.204 Pa at 25°C.