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EC number: 225-268-8 | CAS number: 4748-78-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 Apr 1979 to 03 May 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: Kanpogyo No. 5
- Qualifier:
- according to guideline
- Guideline:
- other: Yakuhatu No. 615
- Qualifier:
- according to guideline
- Guideline:
- other: Kikyoku No. 392
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of the test substance (as cited in study report): 4-Ethylbenzaldehyde
- Molecular formula: C9H10O - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: sludge (not further specified)
- Details on inoculum:
- - Source: Purchased from Chemical Safety Center of Chemicals Inspection & Testing Institute on February 27, 1979 and cultured
- Duration of test (contact time):
- 14 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Remarks:
- 30 mg test substance was used, corresponding to 78.7 mg ThOD
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- Biological Oxygen Demand (BOD)
- Details on study design:
- TEST SYSTEM
- Temperature: 25 °C
- Sludge concentration: 30 mg/L
MEASUREMENTS: O2 demand, test substance concentration
- O2 demand: After 14 days, the biological oxygen demand was determined using an Automatic oxygen consumption meter (Okura Electric Coulometer, Model of the Hokkaido National Industrial Research Institute)
- Test substance concentration: Using a UV spectrophotometer, the pre-degradation concentration and post-degradation concentration of the test substance was measured and the dissappearance was calculated.
DESIGN
- 1 basal respiration flask containing 30 mg/L sludge
- 1 water + sample flask
- 2 test flasks containing 100 mg/L test substance and 30 mg/L sludge
- 2 positive control flasks containing 100 mg/L reference substance and 30 mg/L sludge - Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 80.1
- Sampling time:
- 14 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 98
- Sampling time:
- 14 d
- Remarks on result:
- other: results obtained using UV spectrophotometer
- Details on results:
- The BOD of the test substance was determined to be 66.0 mg after 14 days.
- Results with reference substance:
- The degree of biodegradation of the reference substance after 7 days was 65.6 %.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
Reference
Sample |
BOD (mg) |
Basal respiration (B) |
3.0 |
Sludge + sample (BOD) |
66.0 |
Degradation% = (BOD – B)/ThOD x100 = (66.0-3.0)/78.7 x100 = 80.1%
Description of key information
The test substance was determined to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The biodegradation potential of the substance in water was determined in a non-GLP preliminary screening study in accordance to Japanese national guidelines (Niigata Research Laboratory, 1979). In this study, 100 mg/L test substance was inoculated with sludge for 14 days under aerobic conditions. During the incubation period the biological oxygen demand (BOD) was measured and thereafter compared to the theoretical uptake (ThOD), to determine the degree of biodegradation. Furthermore, Using a UV spectrophotometer, the pre-degradation concentration and post-degradation concentration of the test substance was measured and the dissappearance was calculated. After the 14-day incubation period 80.1% of the substance was found to be biodegraded by oxygen demand. Test substance UV spectrophotometry showed a disappearance of 98% of the test substance at study termination. Based on these findings, the test substance is determined to be readily biodegradable.
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