Iodo(triphenylphosphino)copper

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

2003

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Considering the structural similarities of the substances "Iodo(triphenylphosphino)copper" and "Iodotris(triphenylphosphino)copper" and the almost identical physical and chemical properties, especially partition coefficients and water solubilites, it can be expected that these substances will show quite similar behaviour with respect to short-term aquatic toxicity to aquatic invertebrates, too.

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

other: OECD 202

GLP compliance:

yes

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 219001
- Expiration date of the lot/batch: Sept. 23rd 2003

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in a closed polyethylene vessel at room temperature.

Analytical monitoring:

no

Test organisms (species):

other aquatic crustacea: DM

Details on test organisms:

Daphnia magna is bred in the LAUS GmbH throughout the year. The animals are kept
for the use in toxicity tests. They multiply by parthenogenesis, thus being genetically
identical. The holding is performed similar to the method described in EN I SO 6341 , following
SOP 115 002 01 (,,Zucht und Halterung von Daphnia magna STRAUS"), edition 5, adopted Jan. 13th, 2003.

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

48 h

Hardness:

200 mg CaCO3/L

Test temperature:

20 ± 2 °C

pH:

ca. 8

Dissolved oxygen:

8.3 to 8.6 mg/l

Conductivity:

246 μS/cm

Reference substance (positive control):

yes

Duration:

24 h

Dose descriptor:

EC50

Effect conc.:

1 000 mg/L

Nominal / measured:

nominal

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

1 000 mg/L

Nominal / measured:

nominal

Duration:

48 h

Dose descriptor:

EC100

Effect conc.:

> 1 000 mg/L

Nominal / measured:

nominal

Duration:

48 h

Dose descriptor:

NOEC

Effect conc.:

> 1 000 mg/L

Nominal / measured:

nominal

Validity criteria fulfilled:

yes

Conclusions:

In the initial experiment, three concentrations of the test item in a geometric series
(spaced by factor 10, the highest being the saturation concentration) were used. For
each concentration, twenty daphnia were exposed to the test item for 48 hours.
At 100% saturation, 20% of the daphnia were immobilized, at 10 and 1 % saturation, no
daphnia were immobilized.
The main study was performed as a limit test using a saturated solution (1000 mg/I
nom.). No daphnia were immobilized in the test.

Executive summary:

The following results for the test item were determined:

48h-EC50i.(species: Daphnia magna) > 1000 mg/L nominal concentration

48h-EC50i,(species: Daphnia magna) > water solubility

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

1 000 mg/L

Additional information

EC50 value is above the solubility limit.