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Diss Factsheets
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EC number: 945-989-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02 April to 20 October 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Kyoeisha Chemical Co. Ltd./ Bx 6021874
- Expiration date of the lot/batch: 18 february 2019
- Purity test date: 18 february 2017
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature in original container away from heat or sunlight.
- Stability under test conditions:
- Solubility and stability of the test substance in the solvent/vehicle:
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium:
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: none
- Preliminary purification step (if any):
- Final dilution of a dissolved solid, stock liquid or gel:
- Final preparation of a solid:
FORM AS APPLIED IN THE TEST (if different from that of starting material)
TYPE OF BIOCIDE/PESTICIDE FORMULATION (if applicable)
OTHER SPECIFICS:
- measurement of pH, osmolality, and precipitate in the culture medium to which the test chemical is added:
- other information: - Analytical monitoring:
- yes
- Remarks:
- It will be difficult due to the very low water soulbilty
- Details on sampling:
- 0, 24 and 48 hours
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: A 100 mg of Reaction mass N, N’-bis [2-(octadecanoylamino) ethyl] decanediamide and N, N’-bis [2-(hexadecanoylamino) ethyl] decanediamide was transferred into a 10 mL volumetric flask and the volume was made up with DMF, this was sonicated for 1 h and then centrifuged at 14000 rpm for 10 minutes to obtain the nominal concentration of 10.0 mg/mL (stock A). A 10 µL volume (Stock A) was transferred using a micropipette and diluted to 100 mL with reconstituted water in glass beakers of 600 mL capacity to obtain the nominal test concentration of 1.0 mg Reaction mass N, N’-bis [2-(octadecanoylamino) ethyl] decanediamide and N, N’-bis [2-(hexadecanoylamino) ethyl] decanediamide/L.
- Eluate: DMF
- Differential loading:
- Controls: For the vehicle control, 10 µL of DMF diluted to 100 mL with reconstituted water in glass beakers of 600 mL capacity was used.
- Chemical name of vehicle (organic solvent, emulsifier or dispersant):
- Concentration of vehicle in test medium (stock solution and final test solution(s) or suspension(s) including control(s)):
- Evidence of undissolved material (e.g. precipitate, surface film, etc.): no
- Other relevant information: - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain/clone: no data
- Justification for species other than prescribed by test guideline: Daphnia magna was selected as the test system because it plays an important role as a food chain organism. It has high sensitivity to chemicals in the aquatic ecosystem and is recommended by the OECD and other regulatory authorities. The results of the study are valuable in predicting the acute toxicity of the test item in aquatic ecosystems.
- Age at study initiation (mean and range, SD): <24h
- Weight at study initiation (mean and range, SD): n/a
- Length at study initiation (length definition, mean, range and SD): 48h
- Stage and instar at study initiation: 2nd instar
- Method of breeding: Parthenogenesis
- Source: Laboratory of Ecotoxicology, Jai Research Foundation
- Age of parental stock (mean and range, SD):
- Feeding during test no
- Food type: live algal cells (Pseudokirchneriella subcapitata).
- Amount:
- Frequency:
ACCLIMATION
- Acclimation period: 48h
- Acclimation conditions (same as test or not): Yes
- Type and amount of food: live algal cells (Pseudokirchneriella subcapitata).
- Feeding frequency:
- Health during acclimation (any mortality observed): no mortality
QUARANTINE (wild caught)
- Duration:
- Health/mortality:
METHOD FOR PREPARATION AND COLLECTION OF EARLY INSTARS OR OTHER LIFE STAGES, INCLUDING CULTURING CONDITIONS: - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- Standard study duration.
- Post exposure observation period:
- No
- Hardness:
- 140 and 250 mg/L as CaCO3
- Test temperature:
- 20 ± 2 °C
- pH:
- 6.0 to 9.0
- Dissolved oxygen:
- ≥ 3 mg/L in control and test vessels
- Salinity:
- N/A
- Nominal and measured concentrations:
- currently less than the water solubility of < 0.00022 mg/L
- Reference substance (positive control):
- yes
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: limit of water solubility
- Validity criteria fulfilled:
- yes
- Conclusions:
- LD50 is < 0.00022 mg/L due to the limit of solubility, no effects observed.
Reference
Description of key information
LD50 is < 0.00022 mg/L due to the limit of solubility, no effects observed at the limit of water solubilty
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.