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EC number: 292-772-2 | CAS number: 90990-11-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
No study on ready biodegradability is available for fatty acids,
C18-22. Therefore, read across from the key studies of the main
constituents of the blend was performed. According to the Substance
Identity Profile stearic acid (C18), eicosanoic acid (C20) and
docosanoic acid (C22) are the most representative structures for fatty
acids, C18-22.
Therefore the available experimental data as well as the QSAR prediction
on ready biodegradability for stearic acid (CAS 57-11-4), eicosanoic
acid (CAS 506-30-9) and docosanoic acid (CAS 112-85-6) were considered
to deduce the biodegradability of fatty acids, C18-22.
Stearic acid, saturated was tested by Bogers (1989) for ready
biodegradability according to OECD 301B and GLP. At concentrations of 10
and 20 mg/L the determined degradation values were 72% and 71%,
respectively at test termination (28 d). The pass criterion for ready
biodegradability (60% degradation reached within 10 days once exceeded
10% degradation) was barely missed. However, the sampling interval was
not as small as recommended by the OECD guideline which might have led
to the barely missing of the 10-day window.
The failure of the 10-day window in biodegradation tests with fatty
acids due to the low water solubility/bioavailability as well as to the
inappropriate sampling intervals were already recognized and discussed
within the framework of the SIDS Initial Assessment Report for the
Category “Aliphatic Acids” (OECD, 2009) and judged not to preclude the
ready biodegradability of the fatty acids.
Reliable results of the QSAR model BIOWIN v.4.10 (EPI Suite, 2010) predict ready biodegradability for eicosanoic acid. This method is based on the application of Bayesian analysis to ready biodegradation data for chemicals, derived collectively from all six OECD301 test methods plus OECD310.
Ready and inherent biodegradability of
docosanoic acid were tested by the Japanese Ministry for the Environment
(MOE, 1997). At a concentration of 100 mg/L the substance biodegrades up
to 48 - 56% (BOD) after 28 days according to OECD 301C. In the inherent
biodegradation test according to OECD 302C, the substance was tested at
a concentration of 30 mg/L resulting in biodegradation rates of
docosanoic acid up to 79 - 96% (BOD) after 28 days.
Results of the QSAR model BIOWIN v.4.10 (EPI Suite, 2013)
predict ready biodegradability for docosanoic acid. This method is based
on the application of Bayesian analysis to readily biodegradation data
for chemicals, derived collectively from all six OECD301 test methods
plus OECD310.
Finally, the unsaturated fatty acid
docosenoic acid with a chain length of C22 was found to be readily
biodegradable in a biodegradation test similar to OECD 301 D (Closed
Bottle Test) (Richterich and Mühlberg, 2001). The read across substance
docosenoic acid (C22:1, CAS 112-86-7) was inoculated with suspended
garden mould for 30 days. Based on the oxygen consumption biodegradation
on day 5, 15 and 30 was 40 %, 77 % and 90 %, respectively. Therefore, it
can be concluded, that docosenoic acid, a C22:1 fatty acid, is readily
biodegradable.
Based on the substance identity profile of fatty acids, C18-22 and on the presented data of the main constituents / read across substances it is justified to conclude that the substance is readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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