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EC number: 212-975-1 | CAS number: 894-93-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Data source
Referenceopen allclose all
- Reference Type:
- other: EPISuite calculation
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
- Reference Type:
- other: Estimation software
- Title:
- Estimation Programs Interface Suite for Microsoft Windows, v4.11
- Author:
- US EPA
- Year:
- 2 012
- Bibliographic source:
- United States Environmental Protection Agency, Washington, DC, USA
Materials and methods
- Principles of method if other than guideline:
- Prediction of ready biodegradability based on EPI Suite v4.10 BIOWIN v4.10.
- GLP compliance:
- no
Test material
- Reference substance name:
- 1-[[(2-hydroxyphenyl)imino]methyl]-2-naphthol
- EC Number:
- 212-975-1
- EC Name:
- 1-[[(2-hydroxyphenyl)imino]methyl]-2-naphthol
- Cas Number:
- 894-93-9
- Molecular formula:
- C17H13NO2
- IUPAC Name:
- 1-[(1E)-[(2-hydroxyphenyl)imino]methyl]naphthalen-2-ol
Constituent 1
Results and discussion
% Degradationopen allclose all
- Remarks on result:
- other: Ready biodegradability prediction: Substance is not readily biodegradable.
- Remarks on result:
- other: Biowin1: Biodegrades fast; Biowin2: Biodegrades fast; Biowin3: Weeks-Months; Biowin4: Days-Weeks; Biowin5: Does Not Biodegrade Fast; BIOWIN6: Does Not Biodegrade Fast
Any other information on results incl. tables
BIOWIN v4.10 Results
Biowin1 (Linear Model Prediction) : Biodegrades Fast
Biowin2 (Non-Linear Model Prediction): Biodegrades Fast
Biowin3 (Ultimate Biodegradation Timeframe): Weeks-Months
Biowin4 (Primary Biodegradation Timeframe): Days-Weeks
Biowin5 (MITI Linear Model Prediction) : Does Not Biodegrade Fast
Biowin6 (MITI Non-Linear Model Prediction): Does Not Biodegrade Fast
Biowin7 (Anaerobic Model Prediction): Does Not Biodegrade Fast
Ready Biodegradability Prediction: NO
TYPE |
NUM |
Biowin1 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.1158 |
0.2316 |
MolWt |
* |
Molecular Weight Parameter |
|
-0.1253 |
Const |
* |
Equation Constant |
|
0.7475 |
RESULT |
Biowin1 (Linear Biodeg Probability) |
|
0.8538 |
TYPE |
NUM |
Biowin2 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.9086 |
1.8172 |
MolWt |
* |
Molecular Weight Parameter |
|
-3.7388 |
RESULT |
Biowin2 (Non-Linear Biodeg Probability) |
|
0.7478 |
A Probability Greater Than or Equal to 0.5 indicates --> Biodegrades Fast
A Probability Less Than 0.5 indicates --> Does NOT Biodegrade Fast
TYPE |
NUM |
Biowin3 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.0564 |
0.1128 |
MolWt |
* |
Molecular Weight Parameter |
|
-0.5819 |
Const |
* |
Equation Constant |
|
3.1992 |
RESULT |
Biowin3 (Survey Model - Ultimate Biodeg) |
|
2.7301 |
TYPE |
NUM |
Biowin4 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.0397 |
0.0794 |
MolWt |
* |
Molecular Weight Parameter |
|
-0.3799 |
Const |
* |
Equation Constant |
|
3.8477 |
RESULT |
Biowin4 (Survey Model - Primary Biodeg) |
|
3.5472 |
Result Classification: 5.00 -> hours 4.00 -> days 3.00 -> weeks
(Primary & Ultimate) 2.00 -> months 1.00 -> longer
TYPE |
NUM |
Biowin5 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.0642 |
0.1285 |
Frag |
1 |
Aromatic-CH |
-0.0098 |
-0.0098 |
Frag |
10 |
Aromatic-H |
0.0082 |
0.0822 |
MolWt |
* |
Molecular Weight Parameter |
|
-0.7833 |
Const |
* |
Equation Constant |
|
0.7121 |
RESULT |
Biowin5 (MITI Linear Biodeg Probability) |
|
0.1297 |
TYPE |
NUM |
Biowin6 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.4884 |
0.9768 |
Frag |
1 |
Aromatic-CH |
0.2624 |
0.2624 |
Frag |
10 |
Aromatic-H |
0.1201 |
1.2014 |
MolWt |
* |
Molecular Weight Parameter |
|
-7.6011 |
RESULT |
Biowin6 (MITI Non-Linear Biodeg Probability) |
|
0.0669 |
A Probability Greater Than or Equal to 0.5 indicates --> Readily Degradable
A Probability Less Than 0.5 indicates --> NOT Readily Degradable
TYPE |
NUM |
Biowin7 FRAGMENT DESCRIPTION |
COEFF |
VALUE |
Frag |
2 |
Aromatic alcohol [-OH] |
0.0807 |
0.1614 |
Frag |
1 |
Aromatic-CH |
0.0331 |
0.0331 |
Frag |
10 |
Aromatic-H |
-0.0954 |
-0.9543 |
Const |
* |
Equation Constant |
|
0.8361 |
RESULT |
Biowin7 (Anaerobic Linear Biodeg Prob)
|
|
0.0763 |
A Probability Greater Than or Equal to 0.5 indicates --> Biodegrades Fast
A Probability Less Than 0.5 indicates --> Does NOT Biodegrade Fast
Ready Biodegradability Prediction: (YES or NO)
----------------------------------------------
Criteria for the YES or NO prediction: If the Biowin3 (ultimate survey
model) result is "weeks" or faster (i.e. "days", "days to weeks", or
"weeks" AND the Biowin5 (MITI linear model) probability is >= 0.5, then
the prediction is YES (readily biodegradable). If this condition is not
satisfied, the prediction is NO (not readily biodegradable). This method
is based on application of Bayesian analysis to ready biodegradation data
(see Help). Biowin5 and 6 also predict ready biodegradability, but for
degradation in the OECD301C test only; using data from the Chemicals
Evaluation and Research Institute Japan (CERIJ) database.
Applicant's summary and conclusion
- Interpretation of results:
- not readily biodegradable
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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