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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The study was conducted between 13 September 2000 and 7 December 2000.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Specific details on test material used for the study:
Identity: ST463.
Appearance: magenta powder
Storage conditions: room temperature
Batch number: 6558
Expiry date: August 2001
Purity: 99.4%
Date received: 1 August 2000
Key result
Water solubility:
< 0.1 mg/L
Conc. based on:
test mat.
Incubation duration:
24 h
Temp.:
20 °C
pH:
>= 6.1 - <= 6.8
Details on results:
The detector calibration was found to be linear over the range 0 to 5 mg/l of standard solutions in dimethyl sulphoxide with a regression coefficient of 1.0000.

The table 'measurements of water solubility at 20°C' presents a summary of the results of the test and shows that the water solubility of ST463 is less than 0.1 mg/l as sample absorbance values were lower than that of the lowest calibration standard.

Measurements of water solubility at 20°C

Sample Identity

Time (days)

Absorbance

Concentration (mg/l)

Mean Concentration (mg/l)

pH

Held at 30°C

Equilibrated at 20°C

1A, 1B

1

1

0.009, 0.008

<0.1, <0.1

<0.1

6.4, 6.8

2A, 2B

2

1

0.001, 0.000

<0.1, <0.1

<0.1

6.7, 6.4

3A, 3B

3

1

0.000, 0.000

<0.1, <0.1

<0.1

6.1, 6.1

Water solubility = < 0.1 mg/l

Conclusions:
The water solubility of test substane was found to be less than 0.1 mg/l.
Executive summary:

The water solubility of the test substance was determined using the flask method. The study was conducted to EEC Method A6 and OECD Method No. 105.

The water solubility of test substance was found to be less than 0.1 mg/l.

Description of key information

The water solubility of the test substance was determined using the flask method. The study was conducted to EEC Method A6 and OECD Method No. 105.

The water solubility of test substance was found to be less than 0.1 mg/l.

Key value for chemical safety assessment

Water solubility:
0.1 mg/L
at the temperature of:
30 °C

Additional information