Registration Dossier

Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

Currently viewing:

Administrative data

Endpoint:
biodegradation in water: simulation testing on ultimate degradation in surface water
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING :
In accordance with Column 2 of Annex IX section 9.2.1.2 of REACH, the study does not need to be conducted if the substance is readily biodegradable.
The substance was tested according to OECD 301C and after 28 days 36% degradation was reported and therefore the substance is not identified as readily biodegradable.
However, hydrolysis of the substance has been identified as the main route of degradation (abiotic). Results of an hydrolysis as function of pH study (OECD) showed the estimated half-life of the substance at 25°C to be less than 2 minutes at pH 4, 7 and 9.
It is therefore considered the a simulation testing on ultimate degradation in surface water will provide little additional information since rapid degradation by hydrolysis is already assumed.
In addiiton, the hydrolysis study proposed the hydrolysis product to be Hydroxyethyl sulphate [Molecular weight: 142.1; Smiles: OCCOS(=O)(=O)O]. This hydrolysis product is predicted to be readily biodegradable using EPISUITE model BIOWIN v4.10.
The chemical safety assessment does not indicate the need to investigate further the degradation of the substance and its degradation products.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion