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EC number: 276-075-0 | CAS number: 71839-91-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-h semi-static acute toxicity test (Institute of industrial organic chemistry, 2017) on neonates (< 24 h old) of Daphnia magna was performed under GLP conditions according to OECD 202 (2004). The EC50 value of the test item was determined to be higher than 6.16 mg/L after 48 hours.
Key value for chemical safety assessment
Additional information
A 48-h semi-static acute toxicity test (Institute of industrial organic chemistry, 2017) on neonates (< 24 h old) of Daphnia magna was performed under GLP conditions according to OECD 202 (2004). The test was performed with the nominal concentrations: 140, 64, 29, 13, 6.0, 2.7 and 0 (control) mg/L. The highest test item concentration was prepared by mixing an appropriate amount of the test item with deionized water. The mixture and the control (deionized water) were mechanically shaken for 72 hours (30 ºC, 90 rpm, darkness). After shaking appropriate amounts of stock solutions for preparation of the ISO test water were added into the mixture and the control in order to obtain ISO test water. Lower test item concentrations were prepared by sequential dilutions with ISO test water. The test item concentrations and the control were left for settling phase (2h, no shaking, room temperature). The content of the main ingredient in the test item concentration was determined with a validated spectrophotometric method. Each sample in a volume of 10 mL (control sample, test sample and sample fortified with the standard) was chemically determined at exposure initiation (fresh) and at renewal (24h – old from separate replicates exposed under test conditions) were chemically determined. Moreover, samples of the highest and the lowest test item concentration and the control at renewal (fresh) and at exposure termination renewal (24h – old from separate replicates exposed under test conditions) were determined. Each sample of 10 mL volume ( i.e. control sample, test sample, sample fortified with standard) was directly analyzed without previous pretreatment. At exposure initiation of the test (fresh), the measured concentrations were determined to be 2.8, 5.7, 13.1, 27.8, 58.2 and 126.5 mg/L. After 24 hours (old), the measured concentrations were determined to be 91.7, 88.9, 97.3, 94.7, 90.6 and 91.1 mg/L. After 24 hours of the exposure (fresh), the measured concentrations were determined to be 2.4 and 123.3 mg/L. At the exposure termination (24 h-old) the measured concentrations were determined to be 2.2 and 123.1 mg/L. At exposure initiation and at renewal, in fresh test item concentrations, the determined test item concentrations were in the range of 88.1 – 104.9 % of nominal concentration. Therefore, the test item concentrations were prepared correctly. At exposure termination and at renewal, in 24h - old test item concentrations, the determined test item concentrations were in the range of 80.9 – 97.3 % of nominal concentration. Therefore, the test item concentrations were stable under the test conditions. Additionally the blank control was performed with ISO Test water (without the test substance) and the positive control was performed with potassium dichromate. The EC50 based on the nominal concentration of the reference material was determined to be 1.01 mg/L after 24 hours and 0.92 mg/L after 48 hours therefore the validity criteria were fulfilled. The EC50 value of the test item was determined to be higher than 6.16 mg/L after 48 hours.
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