Registration Dossier
Registration Dossier
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EC number: 252-279-5 | CAS number: 34907-26-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Read-across, detail not available
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- The read-across molecules were chosen due to their structural and functional similarities with the target molecule. The worst case is then assesed and adopted as being relevant for the taget molecule. See attached justificaiton for comparison of structure and functionality for EC 202-746-4.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Read across to 2,4-dinitrotoluene
- GLP compliance:
- not specified
- Remarks:
- Data from collection/ handbook, no informaiton on completion date or compliace is available.
Test material
- Reference substance name:
- 2,4-dinitrotoluene
- EC Number:
- 204-450-0
- EC Name:
- 2,4-dinitrotoluene
- Cas Number:
- 121-14-2
- Molecular formula:
- C7H6N2O4
- IUPAC Name:
- 1-methyl-2,4-dinitrobenzene
- Test material form:
- solid
- Details on test material:
- Molecule for read-across studies
Constituent 1
- Specific details on test material used for the study:
- Read across to 2,4-dinitrotoluene, details unavailable
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- not specified
Results and discussion
Effect concentrations
- Key result
- Dose descriptor:
- other: LC50
- Effect conc.:
- 0.05 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: Read across to 2,4-dinitrotoluene
- Remarks:
- Read across to 2,4-dinitrotoluene, study specific details not available.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- LC50 of 0.05 mg/L was recorded for the read-across molecule 2,4-dinitrotoluene. According to this result, it should be classified as an Acute 1 aquatic hazard and Chronic 1 long-term aquatic hazard according to CLP regulation 1272/2008.
N,N,N-trimethyl-nitroanilinium chloride, which is using the molecule 2,4-dinitrotoluene as a read across should therefore be classified as an an Acute 1 aquatic hazard and Chronic 1 long-term aquatic hazard according to CLP regulation 1272/2008. - Executive summary:
LC50 of 0.05 mg/L was recorded for the read-across molecule 2,4-dinitrotoluene. According to this result, it should be classified as an Acute 1 aquatic hazard and Chronic 1 long-term aquatic hazard according to CLP regulation 1272/2008.
N,N,N-trimethyl-nitroanilinium chloride, which is using the molecule 2,4-dinitrotoluene as a read across should therefore be classified as an an Acute 1 aquatic hazard and Chronic 1 long-term aquatic hazard according to CLP regulation 1272/2008.
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