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EC number: 234-764-3 | CAS number: 12032-20-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 September 2016 - 11 May 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- yes
- Remarks:
- The preliminary test was not performed as the particle size was clearly lower than 1 mm.
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: NFX11-507 (1989)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187 CIPAC Handbook K (2003)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The particle size distribution determination using the CIPAC MT187 method did not follow the GLP principles.
- Type of method:
- other: both sieving and laser diffraction methods were used
- Type of distribution:
- other: volumetric and counted distributions were given
- Remarks on result:
- other: The results are summarised underneath
- Key result
- Percentile:
- D10
- Mean:
- 0.271 µm
- Remarks on result:
- other: number based distribution
- Key result
- Percentile:
- D50
- Mean:
- 0.424 µm
- Remarks on result:
- other: number based distribution
- Key result
- Percentile:
- D90
- Mean:
- 0.978 µm
- Remarks on result:
- other: number based distribution
- Key result
- Percentile:
- D10
- Mean:
- 1.45 µm
- St. dev.:
- 0.045
- Remarks on result:
- other: volumetric distribution
- Key result
- Percentile:
- D50
- Mean:
- 5.76 µm
- St. dev.:
- 0.181
- Remarks on result:
- other: volumetric distribution
- Key result
- Percentile:
- D90
- Mean:
- 12.8 µm
- St. dev.:
- 0.532
- Remarks on result:
- other: volumetric distribution
- No.:
- #1
- Size:
- 250 µm
- Distribution:
- 99.9 %
- No.:
- #2
- Size:
- 180 µm
- Distribution:
- 99.7 %
- No.:
- #3
- Size:
- 125 µm
- Distribution:
- 99.6 %
- No.:
- #4
- Size:
- 100 µm
- Distribution:
- 99.5 %
- No.:
- #5
- Size:
- 90 µm
- Distribution:
- 98.9 %
- No.:
- #6
- Size:
- 63 µm
- Distribution:
- 98.8 %
- No.:
- #7
- Size:
- 45 µm
- Distribution:
- 98.7 %
- No.:
- #8
- Size:
- 32 µm
- Distribution:
- 96.6 %
- No.:
- #9
- Size:
- 25 µm
- Distribution:
- 75.7 %
- No.:
- #10
- Size:
- 20 µm
- Distribution:
- 12.6 %
- Conclusions:
- The particle size distribution was determined by sieving according to OECD 110, ISO 13320-1:1999, NFX11-507 guidelines and by laser diffraction using the CIPAC MT 187 method. It was shown that the majority of particles (96.6%) had a size lower than 32 µm. The particle size distribution of the test item in volume and number were found to range approximately from 0.276 µm to 86.4 µm and 0.243 µm to 14.5 µm, respectively. The mean diameter in volume was 6.68 µm, and D10, D50 and D90 were determined to be 1.45 µm, 5.76 µm and 12.8 µm, respectively. The particle size distribution of the test item in number was found to range approximately from 0.243 µm to 14.5 µm, and D10, D50 and D90 were determined to be 0.271 µm, 0.424 µm and 0.978 µm, respectively.
Reference
Particle size distribution (OECD 110, ISO 13320-1:1999, NFX11-507)
It was shown that the majority of particles (96.6%) had a size lower than 32 µm. The cumulated undersize particle fractions per sieve are summarised in the table above. No loss of mass was recorded. The highest aperture size through which 100% of the particles passed was 355 µm.
Particle size distribution by laser diffraction (CIPAC MT 187)
The particle size distribution of the test item in volume was found to range approximately from 0.276 µm to 86.4 µm. The mean diameter in volume was 6.68 µm.
The particle size distribution of the test item in number was found to range approximately from 0.243 µm to 14.5 µm.
Description of key information
The particle size distribution was determined according to OECD 110, ISO 13320 -1:1999, NFX11-507 guidelines (conform GLP) and by laser diffraction using the CIPAC MT 187 method (not conform GLP) (K1, Demangel, 2017).
It was shown that the majority of particles (96.6%) had a size lower than 32 µm. The particle size distribution of the test item in volume determined by laser diffraction was found to range approximately from 0.276 µm to 86.4 µm. The mean diameter in volume dv was 6.68 µm and D10, D50 and D90 were determined to be 1.45 µm, 5.76 µm and 12.8 µm respectively. The particle size distribution of the test item in number was found to range approximately from 0.243 µm to 14.5 µm and D10, D50 and D90 were determined to be 0.271 µm, 0.424 µm and 0.978 µm respectively.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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