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Diss Factsheets
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EC number: 434-280-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
- (Z)-octadec-9-enylamine (CAS 112-90-3): BCF of 1200 is assigned based on an OECD 305 study assessed in the ECHA Committee for Risk Assessment Annex I background document to the opinion proposing harmonized classification and labelling at community level of (Z)-octadec-9-enylamine (December, 2011)
- Dibutyl hydrogen phosphate (CAS 107-66-4):
- Log Kow = 0.57 (below the screening criteria)
- BCF < 6.7 (OECD 305C with common carp)
- Butyl dihydrogen phosphate (CAS 12788-93-1):
- Log Kow = -0.3 (below the screening criteria
- BCF of 3.3 (OASIS Catalogic BCF base-line model DP v.02.07)
- O,O-dihexyl hydrogen dithiophosphate (CAS 78-64-8; AKA Di-n-hexyl dithiophosphoric acid): BCF of 46.8 (OASIS Catalogic BCF base-line model DP v.02.07)
There is no bioaccumulation data for EC 434-280-4. However, conducting a study is not technically possible due to rapid dissociation into the starting materials. Therefore, each of the starting materials (same as the dissociation products) are evaluated for their bioaccumulation potential. The constituent with the highest BCF value is adopted as the key value, which is a BCF of 1200 (dimensionless) for (Z)-octadec-9-enylamine (CAS 112-90-3).
Following is a summary of the BCF values and their source for each of the 4 dissociation products:
The OASIS Catalogic BCF base-line model DP v.02.07 was used for estimating bioaccumulation potential to account for the ionization potential of butyl dihydrogen phosphate and dihexyl hydrogen dithiophosphate. The DP model explicitly estimates the ionization by taking into account Log D/P where D is the distribution coefficient of neutral and ionized species in octanol/water and P is the partition coefficient in octanol/water. D was calculated using ACDLabs software (v.12). The BCF was predicted at multiple environmental pHs, including 4, 7, and 9. In addition, the classic BCF-base line model (v.05.12) was also used to estimate BCF for comparison. Based on domain results (100% in domain) and confirmation of BCF estimates with analog alkyl phosphate esters and dialkyl dithiophosphate esters that have data, the predictions are considered highly reliable.
See the attached for weight of evidence for details and references on the bioaccumulation potential.
Key value for chemical safety assessment
- BCF (aquatic species):
- 1 200
Additional information
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