Registration Dossier
Registration Dossier
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EC number: 285-132-9 | CAS number: 85030-08-6
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- The QSAR prediction is within the domains of applicability of the CATALOGIC 301C model. Both the prediction and the model are validated according to the OECD principles of validation.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Guideline:
- other: OECD 301C
Test material
- Reference substance name:
- Dodecanedioic acid, compound with 2,2',2''-nitrilotriethanol (1:2)
- EC Number:
- 285-132-9
- EC Name:
- Dodecanedioic acid, compound with 2,2',2''-nitrilotriethanol (1:2)
- Cas Number:
- 85030-08-6
- Molecular formula:
- C12H22O4.2C6H15NO3
- IUPAC Name:
- dodecanedioic acid - 2,2',2''-nitrilotriethanol (1:2)
Constituent 1
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 78.1
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Executive summary:
The biodegradation potential of the target substance (TS), Dodecanedioic acid, compound with
2,2',2''-nitrilotriethanol (1:2)’, CAS 85030-08-6, EC 285-132-9, was assessed using the validated
QSAR model
CATALOGIC 301C, developed by the Laboratory of Mathematical Chemistry, Bulgaria. The TS was
modeled as a mixture of five constituents, identified analytically, that together add up to > 99% of its
composition.
The model predicts a 28-day biodegradation of 78% for the target substance, with a primary half-life
of < 1 day and an ultimate half-life of 12.78 days. It can be considered to be readily biodegradable.
Both the prediction and the QSAR model are validated according to the OECD principles of validation
of QSAR predictions. The separately attached QMRF provides all pertinent information about the
QSAR model, including information on its training and validation sets.
The target substance can be assessed as 'readily biodegradable' and the prediction is fully in the
model’s
applicability domain and as such, is reliable and robust and can be used for regulatory purposes.
purposes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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