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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature. Original reference in foreign language.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Biological action of the halogenated derivatives of organic substances as a function of their reactivity
Author:
Eitingon, A.I., Ulanova, I.P.
Year:
1975
Bibliographic source:
Gig. Tr. Prof. Zabol., issue 9, 36-39
Reference Type:
secondary source
Title:
Toxicological Evaluations Vol. 13
Author:
BG Chemie
Year:
1998
Bibliographic source:
Springer-Verlag Berlin Heidelberg, ISBN 3-540-62658-1

Materials and methods

Principles of method if other than guideline:
Determination of LD50 after oral administration to rats.
GLP compliance:
no
Test type:
other: Determination of LD50 after oral administration to rats.

Test material

Constituent 1
Chemical structure
Reference substance name:
Fluorobenzene
EC Number:
207-321-7
EC Name:
Fluorobenzene
Cas Number:
462-06-6
Molecular formula:
C6H5F
IUPAC Name:
fluorobenzene

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
4 399 mg/kg bw
Clinical signs:
other:

Applicant's summary and conclusion