Registration Dossier
Registration Dossier
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EC number: 221-508-0 | CAS number: 3126-80-5
Endpoint summary
Administrative data
Description of key information
Determination of 'Ready' Biodegradability was performed in a Carbon Dioxide (CO2) Evolution Test (Modified Sturm Test) in compliance with the OECD guideline No. 301 B (1992). In addition, the procedures were designed to meet the test methods of the ISO standard 10634, 1995. The study was conducted according to GLP.The test item was tested in duplicate at a target concentration of 16.5 mg/L, corresponding to 12 mg TOC/L. The organic carbon content was based on the molecular formula. The Theoretical CO2 production (ThCO2) of the test substance was calculated to be 2.63 mg CO2/mg.The relative biodegradation values calculated from the measurements performed during the test period revealed 13% and 0% biodegradation of test item (based on ThCO2), for the duplicate bottles tested. Thus, the criterion for ready biodegradability (at least 60% biodegradation within a 10 -day window) was not met. In conclusion, test substance was not readily biodegradable under the conditions of the modified Sturm test presently performed.
Additional information
Supporting information:
Prediction of tetrakis(2-ethylhexyl) benzene-1,2,4,5-tetracarboxylate is 'Non Readily Biodegradable' using the model Ready Biodegradability Sarpy rule set by Istituto di Ricerche Farmacologiche Mario Negri from VEGA QSAR Model.
Prediction is "biodegrades fast" using BIOWIN 1 and 2 models by EPI Suite software v4.1.
Using Biowin 3 from EPI Suite v4.1 software, the expected ultimate biodegradation timeframe is days to weeks
Using Biowin 4 from EPI Suite v4.1 software, the expected primary biodegradation timeframe is days
Using Biowin 5 from EPI Suite v4.1 software, the substance is expected to be readily biodegradable.
Using Biowin 6 from EPI Suite v4.1 software, the substance is expected to be readily biodegradable.
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