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EC number: 248-329-0 | CAS number: 27214-38-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Data on the aquatic toxicity of Glycerol monomyristate (CAS 27214-38-6) are available for aquatic invertebrates and algae. In order to assess the acute toxicity to fish and the toxicity to microorganisms read-across to the structurally related substances Glycerides, C12-18 mono- and di- ( (CAS 91052-49-2), Glycerides, C12-18 di- and tri- (CAS 91744-28-4) and Docosanoic acid, ester with 1,2,3-propanetriol (CAS 77538-19-3) was conducted to fulfil the standard information requirements. In accordance with Article 13 (1) of Regulation (EC) No 1907/2006, "information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI are met.” In particular for aquatic toxicity, information shall be generated whenever possible by means other than vertebrate animal tests, which includes the use of information from structurally related substances (grouping or read-across). According to Annex XI, Item 1.5, of Regulation (EC) No 1907/2006 substances can be considered to be similar if their physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity.
The target and source substances are esters of a tri-functional alcohol (glycerol) with one or more carboxylic (fatty) acid(s) chain(s). The alcohol moiety (glycerol) is common to allanalogue substances.The fatty acid moiety comprises linear saturated carbon chain lengths from C12-C18 (even-numbered) and C22 bound to the alcohol, resulting in mono-, di-, and triesters.The target and the source substances are characterised by comparable physico-chemical properties and an analogue environmental fate. Please refer to the analogue justification for more details on the read-across approach.
The available studies on the acute toxicity of the source substance to fish determined no detrimental effects on fish. The determined LL50 (96 h) forGlycerides, C12-18 mono- and di- (CAS 91052-49-2) was > 2.7 mg/L (measured). For the source substance of Docosanoic acid, ester with 1,2,3-propanetriol (CAS 77538-19-3) a LC50 (96 h) > 10000 mg/L (nominal concentration) was reported.
The available study on the toxicity of the target substanceGlycerol monomyristate to aquatic invertebrates determined noacute toxicity to Daphnia magna (EC50 (48 h) > 0.69 mg/L; measured, arithm. mean). In the available study on the toxicity ofGlycerol monomyristate to aquatic algae anErC50 (72 h) >0.28 mg/L (meas. arith. mean) was determined (ErC10 (72 h) >0.28 mg/L (meas. arith. mean)).
Data on the toxicity to microorganisms are available for the source substance Glycerides, C12-18 di- and tri- (CAS 91744-28-4). Adverse effects of the substances to microorganisms were not observed.
The available acute toxicity data on the target and the source substances demonstrate that acute toxic effects of the target substance Glycerol monomyristate (CAS 27214-38-6) are not likely.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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