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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
data from handbook or collection of data
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
The water solubility of p-hydroxyphenylacetic acid is determined.
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
- Name of test material: p-hydroxyphenylacetic acid
- IUPAC name: 4-Hydroxyphenylacetic Acid
- Molecular formula: C8H8O3
- Molecular weight: 152.148 g/mole
- Smiles : c1(ccc(O)cc1)CC(O)=O
- Inchl: 1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
- Substance type: Organic
- Physical state: Solid crystalline powder (off white)
Key result
Water solubility:
17 300 mg/L
Conc. based on:
test mat.
Temp.:
22 °C
Remarks on result:
other: Very soluble in water
Conclusions:
The water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C.
Executive summary:

Based on available data from authoritative database, the water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C. Hence on the basis of obtained value the given chemical is considered to be very soluble in water.

Description of key information

The water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C.

Key value for chemical safety assessment

Water solubility:
17 300 mg/L
at the temperature of:
22 °C

Additional information

Based on available data from authoritative database, the water solubility of p-hydroxyphenylacetic acid is determined to 17300 mg/L at 22 °C.

Other supporting data from handbook and authoritative database, also supported the selected key study and exhibited the water solubility of p-hydroxyphenylacetic acid as 160000 mg/L and 60700 mg/L at 25 °C respectively.

Hence on the basis of obtained values the given chemical is considered to be very soluble in water.